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Gene Expression Data
Assay Details
Assay
Reference: J:326575 Tsume-Kajioka M, et al., BET proteins are essential for the specification and maintenance of the epiblast lineage in mouse preimplantation embryos. BMC Biol. 2022 Mar 9;20(1):64
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7316604
Gene symbol: Gata6
Gene name: GATA binding protein 6
Antibody: anti-Gata6 (AF1700)
Assay notes: Two antibodies were described, but the one used in this assay was not detailed. Antibody name MGI:6286278 may have been used in this assay.
Results
Specimen 3E: embryonic day 3.0 (more )
Note: 16 cell stage
Structure Level Pattern Image Note
TS4: compacted morula Present 3E
Specimen S1C',C'': embryonic day 3.5 (more )
Note: Double labeled: green - Gata6; magenta - Nanog (assay MGI:7316599).
Structure Level Pattern Image Note
TS5: inner cell mass Present Regionally restricted S1C' , S1C'' Co-expression with Nanog in some cells; mostly mutually exclusive expression.
Specimen S8A,C,C': embryonic day 4.25 (more )
Note: Triple labeled: green - Gata6; magenta - Nanog (assay MGI:7316599); yellow - Cdx2 (assay MGI:7316605).
Structure Level Pattern Image Note
TS6: primitive endoderm Present Regionally restricted S8C'' , S8A , S8C Expression in polarized cells forming epithelium along blastocyst cavity.
Specimen S8B,D,D'': embryonic day 4.25; Brd4tm1a(EUCOMM)Wtsi/Brd4tm1a(EUCOMM)Wtsi, Tmem163Tg(ACTB-cre)2Mrt/0 (more )
Note: Conditional mutant. Triple labeled: green - Gata6; magenta - Nanog (assay MGI:7316599); yellow - Cdx2 (assay MGI:7316605).
Structure Level Pattern Image Note
TS6: primitive endoderm Present Regionally restricted S8D , S8D'' , S8B Expression in cells appearing closer to outer trophectoderm layer, failing to correctly form single epithelial layer.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory