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Gene Expression Data
Assay Details
Assay
Reference: J:173286 Long JE, et al., Dlx1&2 and Mash1 transcription factors control MGE and CGE patterning and differentiation through parallel and overlapping pathways. Cereb Cortex. 2009 Jul;19 Suppl 1:i96-106
Assay type: RNA in situ
MGI Accession ID: MGI:7316460
Gene symbol: Nkx2-1
Gene name: NK2 homeobox 1
Probe: Nkx2-1 probe26
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 2OO: embryonic day 15.5 (more )
Note: The genetic background of the control specimen was either wild type or heterozygous.
Structure Level Pattern Image Note
TS23: globus pallidus Present 2OO
TS23: medial ganglionic eminence Present Regionally restricted 2OO Expression is in progenitor cells.
Specimen 2OO': embryonic day 15.5; Del(2Dlx1-Dlx2)1Jlr/Del(2Dlx1-Dlx2)1Jlr (more )
Structure Level Pattern Image Note
TS23: medial ganglionic eminence Present 2OO' Expression increased in this mutant compared to controls.
Specimen 2PP: embryonic day 15.5 (more )
Note: The genetic background of the control specimen was either wild type or heterozygous.
Structure Level Pattern Image Note
TS23: caudal ganglionic eminence Present 2PP
Specimen 2PP': embryonic day 15.5; Del(2Dlx1-Dlx2)1Jlr/Del(2Dlx1-Dlx2)1Jlr (more )
Structure Level Pattern Image Note
TS23: caudal ganglionic eminence Present 2PP' Expression is in ectopia that form in this mutant in a caudal position within the caudal ganglionic eminence.
Specimen S2F: embryonic day 15.5 (more )
Note: The genetic background of the control specimen was either wild type or heterozygous.
Structure Level Pattern Image Note
TS23: caudal ganglionic eminence Present S2F
Specimen S2F': embryonic day 15.5; Del(2Dlx1-Dlx2)1Jlr/Del(2Dlx1-Dlx2)1Jlr (more )
Structure Level Pattern Image Note
TS23: caudal ganglionic eminence Present S2F' Expression is in ectopia that form in this mutant in a caudal position within the caudal ganglionic eminence.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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