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Gene Expression Data
Assay Details
Assay
Reference: J:173286 Long JE, et al., Dlx1&2 and Mash1 transcription factors control MGE and CGE patterning and differentiation through parallel and overlapping pathways. Cereb Cortex. 2009 Jul;19 Suppl 1:i96-106
Assay type: RNA in situ
MGI Accession ID: MGI:7316419
Gene symbol: Pbx1
Gene name: pre B cell leukemia homeobox 1
Probe: Pbx1 probe3
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 1OO: embryonic day 15.5 (more )
Note: The genetic background of the control specimen was either wild type or heterozygous.
Structure Level Pattern Image Note
TS23: lateral ganglionic eminence Present 1OO
TS23: medial ganglionic eminence Weak Regionally restricted 1OO Expression is in the ventricular and subventricular zone.

Specimen 1OO': embryonic day 15.5; Del(2Dlx1-Dlx2)1Jlr/Del(2Dlx1-Dlx2)1Jlr (more )
Structure Level Pattern Image Note
TS23: lateral ganglionic eminence Present 1OO' Expression is reduced in this mutant compared to controls.
TS23: medial ganglionic eminence Present 1OO' Expression is reduced in this mutant compared to controls.

Specimen 1PP: embryonic day 15.5 (more )
Note: The genetic background of the control specimen was either wild type or heterozygous.
Structure Level Pattern Image Note
TS23: caudal ganglionic eminence Present 1PP

Specimen 1PP': embryonic day 15.5; Del(2Dlx1-Dlx2)1Jlr/Del(2Dlx1-Dlx2)1Jlr (more )
Structure Level Pattern Image Note
TS23: caudal ganglionic eminence Present 1PP' Expression is reduced in this mutant compared to controls.

Specimen S2I: embryonic day 15.5 (more )
Note: The genetic background of the control specimen was either wild type or heterozygous.
Structure Level Pattern Image Note
TS23: caudal ganglionic eminence Present S2I

Specimen S2I': embryonic day 15.5; Del(2Dlx1-Dlx2)1Jlr/Del(2Dlx1-Dlx2)1Jlr (more )
Structure Level Pattern Image Note
TS23: caudal ganglionic eminence Present S2I' Expression is in ectopia that form in this mutant. Expression is reduced in this mutant compared to controls.

Specimen Table 1: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: ganglionic eminence Present


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory