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Gene Expression Data
Assay Details
Assay
Reference: J:173286 Long JE, et al., Dlx1&2 and Mash1 transcription factors control MGE and CGE patterning and differentiation through parallel and overlapping pathways. Cereb Cortex. 2009 Jul;19 Suppl 1:i96-106
Assay type: RNA in situ
MGI Accession ID: MGI:7316403
Gene symbol: Dlx1
Gene name: distal-less homeobox 1
Probe: Dlx1 probe11
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 1I: embryonic day 15.5 (more )
Note: The genetic background of the control specimen was either wild type or heterozygous.
Structure Level Pattern Image Note
TS23: globus pallidus Present 1I
TS23: lateral ganglionic eminence Present 1I
TS23: medial ganglionic eminence Present Regionally restricted 1I Expression is in the ventricular and subventricular zone.
Specimen 1I': embryonic day 15.5; Del(2Dlx1-Dlx2)1Jlr/Del(2Dlx1-Dlx2)1Jlr (more )
Structure Level Pattern Image Note
TS23: lateral ganglionic eminence Present 1I'
TS23: medial ganglionic eminence Present 1I' Expression is reduced in this mutant compared to controls.
Specimen 1J: embryonic day 15.5 (more )
Note: The genetic background of the control specimen was either wild type or heterozygous.
Structure Level Pattern Image Note
TS23: caudal ganglionic eminence Present 1J
Specimen 1J': embryonic day 15.5; Del(2Dlx1-Dlx2)1Jlr/Del(2Dlx1-Dlx2)1Jlr (more )
Structure Level Pattern Image Note
TS23: caudal ganglionic eminence Present 1J' Expression is reduced in this mutant compared to controls.
Specimen Suppl Table 3 Mash1-/-: embryonic day 15.5; Ascl1tm1And/Ascl1tm1And (more )
Structure Level Pattern Image Note
TS23: caudal ganglionic eminence Present Expression is increased in this mutant compared to controls.
TS23: medial ganglionic eminence Present Expression is increased in this mutant compared to controls.
Specimen Suppl Table 3 Dlx1&2-/-; Mash1-/-: embryonic day 15.5; Ascl1tm1And/Ascl1tm1And, Del(2Dlx1-Dlx2)1Jlr/Del(2Dlx1-Dlx2)1Jlr (more )
Structure Level Pattern Image Note
TS23: caudal ganglionic eminence Present Expression is reduced in this mutant compared to controls.
TS23: medial ganglionic eminence Present Expression is reduced in this mutant compared to controls.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory