Tg(NKX2-5-lacZ)#Kyuhl
Transgene Detail
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| Symbol: |
Tg(NKX2-5-lacZ)#Kyuhl |
| Name: |
transgene insertion, Kyu-Ho Lee |
| MGI ID: |
MGI:7314958 |
| Synonyms: |
Nkx2.5-lacZ-SHF |
| Transgene: |
Tg(NKX2-5-lacZ)#Kyuhl Location: unknown
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| Alliance: |
Tg(NKX2-5-lacZ)#Kyuhl page
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| Transgene Type: |
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Transgenic (Reporter) |
| Mutation: |
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Insertion
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Mutation details: The chicken second heart field (SHF) NK2 homeobox 5 enhancer (cardiac activating region 3 (CAR3); nucleotides 976-3047 after transcriptional start site), was placed downstream of a reporter gene cassette containing the hsp68 promoter, lacZ beta-galactosidase gene and poly(A) signal sequences. The promoter proximal CArG box/Srf binding element (SRE), located around -100 bp upstream of the NKX2-5 transcriptional start site, was placed upstream of the lacZ cassette. Founder information and line numbers were not available. The pound symbol (#) is used when no line is specified and/or lines are pooled.
(J:321164)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:321164 Clark CD, et al., Second heart field-specific expression of Nkx2-5 requires promoter proximal interaction with Srf. Mech Dev. 2020 Jun;162:103615 |
| All: |
1 reference(s) |
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Analysis Tools
