About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:74178 Schuller U, et al., Developmental expression of heterotrimeric G-proteins in the murine cerebellar cortex. Histochem Cell Biol. 2001 Aug;116(2):149-59
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7314902
Gene symbol: Gnao1
Gene name: guanine nucleotide binding protein, alpha O
Antibody: anti-Gnao1 (sc-387)
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen 2A: postnatal day 5 (more )
Structure Cell Type Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Purkinje cell Strong 2A Expression is in the somata and dendrites.
TS28: cerebellum external granule cell layer Moderate 2A Expression is in the outer proliferative part and is absent in the inner premigratory part of the external granule cell layer.
TS28: cerebellum internal granule cell layer Present 2A

Specimen 2B: postnatal day 8 (more )
Structure Cell Type Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Purkinje cell Strong 2B Expression is in the somata and dendrites.
TS28: cerebellum external granule cell layer Present Regionally restricted 2B Expression is in the outer proliferative part and is absent in the inner premigratory part of the external granule cell layer.
TS28: cerebellum internal granule cell layer Present 2B

Specimen 2C: postnatal adult (more )
Structure Cell Type Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Purkinje cell Strong 2C Expression is strong in the soma and is absent in dendrites.
TS28: cerebellum internal granule cell layer Present 2C
TS28: cerebellum molecular layer Present 2C
TS28: cerebellum white matter Absent 2C

Specimen 2D: postnatal adult (more )
Structure Cell Type Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Purkinje cell Strong 2D Expression is strong in the soma and is absent in dendrites.
TS28: cerebellum internal granule cell layer Present 2D
TS28: cerebellum molecular layer Present 2D

Specimen Table 3 P3: postnatal day 3 (more )
Structure Cell Type Level Pattern Image Note
TS27: cerebellum Purkinje cell layer Purkinje cell Strong Expression is strong in the soma and moderate in dendrites.
TS27: cerebellum external granule cell layer Moderate Regionally restricted Expression is in the outer proliferative part and is absent in the inner premigratory part of the external granule cell layer.
TS27: cerebellum internal granule cell layer Weak

Specimen Table 3 P5: postnatal day 5 (more )
Structure Cell Type Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Purkinje cell Strong Expression is strong in the soma and dendrites.
TS28: cerebellum external granule cell layer Moderate Regionally restricted Expression is in the outer proliferative part and is absent in the inner premigratory part of the external granule cell layer.
TS28: cerebellum internal granule cell layer Weak

Specimen Table 3 P8: postnatal day 8 (more )
Structure Cell Type Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Purkinje cell Strong Expression is strong in the soma and dendrites.
TS28: cerebellum external granule cell layer Moderate Regionally restricted Expression is in the outer proliferative part and is absent in the inner premigratory part of the external granule cell layer.
TS28: cerebellum internal granule cell layer Weak

Specimen Table 3 P15: postnatal day 15 (more )
Structure Cell Type Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Purkinje cell Strong Expression is strong in the soma and is absent in dendrites.
TS28: cerebellum internal granule cell layer Moderate
TS28: cerebellum molecular layer Moderate

Specimen Table 3 Adult: postnatal adult (more )
Structure Cell Type Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Purkinje cell Strong Expression is strong in the soma and is absent in dendrites.
TS28: cerebellum internal granule cell layer Moderate
TS28: cerebellum molecular layer Moderate

Specimen not shown: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: cerebellum Present There are no regional differences in expression.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/18/2025
MGI 6.24
The Jackson Laboratory