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Gene Expression Data
Assay Details
Assay
Reference: J:325117 Romero DM, et al., Novel role of the synaptic scaffold protein Dlgap4 in ventricular surface integrity and neuronal migration during cortical development. Nat Commun. 2022 May 18;13(1):2746
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7312152
Gene symbol: Dlgap4
Gene name: DLG associated protein 4
Antibody: Anti-DLGAP4 antibody (ab73285)
Detection system: Secondary antibody coupled to Alexa Fluor 568
Results
Specimen 2b/c: embryonic day 14.5 (more )
Structure Cell Type Level Pattern Image Note
TS22: cerebral cortex ventricular layer radial glial cell Strong Regionally restricted 2b , 2c lower Intense expression at the ventricular surface. Expressed in apical radial glial cells.
TS22: cortical plate neuron Strong 2b , 2c upper
TS22: cerebral cortex intermediate zone Present 2b , 2c upper
TS22: cerebral cortex subventricular zone neural progenitor cell Present 2b , 2c lower Expressed in intermediate progenitors.
Specimen 2d: embryonic day 16.5 (more )
Note: Double labeled: red - Dlgap4; green - Tubb3 (assay MGI:7312159).
Structure Level Pattern Image Note
TS24: cerebral cortex intermediate zone Present 2d merge , 2d Dlgap4
TS24: cerebral cortex subventricular zone Present 2d merge , 2d Dlgap4
TS24: cerebral cortex ventricular layer Present 2d merge , 2d Dlgap4
TS24: cortical plate Present 2d merge , 2d Dlgap4
TS24: ganglionic eminence Present 2d merge , 2d Dlgap4
Specimen 2e upper: embryonic day 16.5 (more )
Note: Double labeled: red - Dlgap4; green - Tubb3 (assay MGI:7312159).
Structure Cell Type Level Pattern Image Note
TS24: cerebral cortex subventricular zone neuron Present 2e upper merge , 2e upper Dlgap4 Co-expressed with Tubb3 in the cell bodies of migrating neurons.
TS24: cerebral cortex ventricular layer Present 2e upper Dlgap4 , 2e upper merge
Specimen 2e lower: embryonic day 16.5 (more )
Note: Double labeled: red - Dlgap4; green - Tubb3 (assay MGI:7312159).
Structure Cell Type Level Pattern Image Note
TS24: cerebral cortex subventricular zone neuron Present 2e lower merge , 2e lower Dlgap4 Co-expressed with Tubb3 in the cell bodies of migrating neurons.
TS24: cerebral cortex ventricular layer Present 2e lower merge , 2e lower Dlgap4
Specimen 2f: embryonic day 14.5 (more )
Note: Double labeled: red - Dlgap4; blue - Eomes (assay MGI:7312161).
Structure Cell Type Level Pattern Image Note
TS22: cerebral cortex subventricular zone neural progenitor cell Present 2f Dlgap4 , 2f f1 , 2f merge Co-expressed with Eomes in intermediate progenitors.
TS22: cerebral cortex ventricular layer radial glial cell Present 2f f1 , 2f Dlgap4 , 2f merge Expressed in radial glial cells (Eomes-).
Specimen S2c: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: cerebral cortex subventricular zone Present S2c upper
TS22: cerebral cortex ventricular layer Present S2c upper
Specimen S3e: embryonic day 14.5 (more )
Note: Double labeled: red - Dlgap4; white - Dlg1 (assay MGI:7312157).
Structure Level Pattern Image Note
TS22: neocortex Present S3e upper Co-expressed with Dlg1.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/16/2024
MGI 6.23 		The Jackson Laboratory