Lamp1 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:245627 Oka M, et al., Arl8b is required for lysosomal degradation of maternal proteins in the visceral yolk sac endoderm of mouse embryos. J Cell Sci. 2017 Oct 15;130(20):3568-3577
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:7311710
Gene symbol:	Lamp1
Gene name:	lysosomal-associated membrane protein 1

Antibody:	anti-Lamp1 (1D4B)
Detection system:	Secondary antibody coupled to Alexa Fluor 488

Results

Specimen 2C/D: embryonic day 8.5 (more

)
Note: Double labeled: green - Lamp1; red - Arl8b (assay MGI:7311717).

Structure	Level	Pattern	Image	Note
TS13: yolk sac endoderm	Present		2C Lamp1 , 2C merge , 2D Lamp1 , 2D merge

Specimen 3I: embryonic day 8.5 (more

)
Note: Double labeled: green - Lamp1; red - Arl8b (assay MGI:7311717).

Structure	Level	Pattern	Image	Note
TS13: yolk sac endoderm	Present		3I merge , 3I Lamp1

Specimen 3J: embryonic day 8.5; Arl8b^{Gt(AK0793)Wtsi}/Arl8b^{Gt(AK0793)Wtsi} (more

)
Note: Double labeled: green - Lamp1; red - Arl8b (assay MGI:7311717).

Structure	Level	Pattern	Image	Note
TS13: yolk sac endoderm	Present		3J merge , 3J Lamp1	The endoderm was filled with enlarged vesicular structures, most of which were stained positive.

Specimen 4F: embryonic day 8.5 (more

)
Note: Double labeled: green - Lamp1; red - IgG.

Structure	Level	Pattern	Image	Note
TS13: yolk sac endoderm	Present		4F	IgG localized to Lamp1-positive vesicles.

Specimen 4G: embryonic day 8.5; Arl8b^{Gt(AK0793)Wtsi}/Arl8b^{Gt(AK0793)Wtsi} (more

)
Note: Double labeled: green - Lamp1; red - IgG.

Structure	Level	Pattern	Image	Note
TS13: yolk sac endoderm	Present		4G	The endoderm was filled with enlarged vesicular structures (IgG+), most of which were stained positive.

Specimen 5C: embryonic day 8.5; Arl8b^tm1Kkon/Arl8b⁺, Tg(Ttr-cre)1Hadj/0 (more

)
Note: Conditional mutant. Double labeled: green - Lamp1; red - Arl8b (assay MGI:7311717).

Structure	Level	Pattern	Image	Note
TS13: yolk sac endoderm	Present		5C Lamp1 , 5C merge

Specimen 5D: embryonic day 8.5; Arl8b^tm1Kkon/Arl8b^tm1Kkon, Tg(Ttr-cre)1Hadj/0 (more

)
Note: Conditional mutant. Double labeled: green - Lamp1; red - Arl8b (assay MGI:7311717).

Structure	Level	Pattern	Image	Note
TS13: yolk sac endoderm	Present		5D merge , 5D Lamp1	Accumulation of Lamp1-positive vesicles was seen.

Specimen 6J: embryonic day 8.5; Arl8b^tm1Kkon/Arl8b⁺, Tg(Ttr-cre)1Hadj/0 (more

)
Note: Conditional mutant. Double labeled: green - Lamp1; red - IgG.

Structure	Level	Pattern	Image	Note
TS13: yolk sac endoderm	Present		6J

Specimen 6K: embryonic day 8.5; Arl8b^tm1Kkon/Arl8b^tm1Kkon, Tg(Ttr-cre)1Hadj/0 (more

)
Note: Conditional mutant. Double labeled: green - Lamp1; red - IgG.

Structure	Level	Pattern	Image	Note
TS13: yolk sac endoderm	Present		6K	Accumulation of Lamp1-positive vesicles was seen.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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