Dkk2 RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:326256 Lee JM, et al., MSX1 Drives Tooth Morphogenesis Through Controlling Wnt Signaling Activity. J Dent Res. 2022 Jul;101(7):832-839
Assay type:	RNA in situ
MGI Accession ID:	MGI:7311647
Gene symbol:	Dkk2
Gene name:	dickkopf WNT signaling pathway inhibitor 2

Results

Specimen 3M (upper): embryonic day 13.75 (more

)

Structure	Level	Pattern	Image	Note
TS21: upper jaw molar mesenchyme	Weak		3M (upper)

Specimen 3N (upper): embryonic day 13.75; Msx1^tm1Rilm/Msx1^tm1Rilm (more

)

Structure	Level	Pattern	Image	Note
TS21: upper jaw molar mesenchyme	Present	Regionally restricted	3N (upper)	Ectopic expression in molar mesenchyme.

Specimen 3O (upper): embryonic day 13.75; Msx1^tm1Rilm/Msx1^tm1Rilm, Sostdc1^tm1Krum/Sostdc1^tm1Krum (more

)

Structure	Level	Pattern	Image	Note
TS21: upper jaw molar mesenchyme	Present		3O (upper)	Expression remained upregulated in molars.

Specimen 3M (lower): embryonic day 13.75 (more

)

Structure	Level	Pattern	Image	Note
TS21: lower jaw molar mesenchyme	Weak		3M (lower)

Specimen 3N (lower): embryonic day 13.75; Msx1^tm1Rilm/Msx1^tm1Rilm (more

)

Structure	Level	Pattern	Image	Note
TS21: lower jaw molar mesenchyme	Present	Regionally restricted	3N (lower)	Ectopic expression in molar mesenchyme.

Specimen 3O (lower): embryonic day 13.75; Msx1^tm1Rilm/Msx1^tm1Rilm, Sostdc1^tm1Krum/Sostdc1^tm1Krum (more

)

Structure	Level	Pattern	Image	Note
TS21: lower jaw molar mesenchyme	Present		3O (lower)	Expression remained upregulated in molars.

Specimen S1A Mx: embryonic day 13.0 (more

)

Structure	Level	Pattern	Image	Note
TS21: upper jaw molar mesenchyme	Ambiguous		S1A Mx

Specimen S1A' Mx: embryonic day 13.0; Msx1^tm1Rilm/Msx1^tm1Rilm (more

)

Structure	Level	Pattern	Image	Note
TS21: upper jaw molar mesenchyme	Present		S1A' Mx	Significantly increased expression in tooth mesenchyme.

Specimen S1A Mn: embryonic day 13.0 (more

)

Structure	Level	Pattern	Image	Note
TS21: lower jaw molar mesenchyme	Ambiguous		S1A Mn

Specimen S1A' Mn: embryonic day 13.0; Msx1^tm1Rilm/Msx1^tm1Rilm (more

)

Structure	Level	Pattern	Image	Note
TS21: lower jaw molar mesenchyme	Present		S1A' Mn	Significantly increased expression in tooth mesenchyme.

Specimen S1B Mx: embryonic day 14.0 (more

)

Structure	Level	Pattern	Image	Note
TS22: upper jaw molar mesenchyme	Ambiguous		S1B Mx

Specimen S1B' Mx: embryonic day 14.0; Msx1^tm1Rilm/Msx1^tm1Rilm (more

)

Structure	Level	Pattern	Image	Note
TS22: upper jaw molar mesenchyme	Present		S1B' Mx	Significantly increased expression in tooth mesenchyme.

Specimen S1B Mn: embryonic day 14.0 (more

)

Structure	Level	Pattern	Image	Note
TS22: lower jaw molar mesenchyme	Ambiguous		S1B Mn

Specimen S1B' Mn: embryonic day 14.0; Msx1^tm1Rilm/Msx1^tm1Rilm (more

)

Structure	Level	Pattern	Image	Note
TS22: lower jaw molar mesenchyme	Present		S1B' Mn	Significantly increased expression in tooth mesenchyme.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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