About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:326256 Lee JM, et al., MSX1 Drives Tooth Morphogenesis Through Controlling Wnt Signaling Activity. J Dent Res. 2022 Jul;101(7):832-839
Assay type: RNA in situ
MGI Accession ID: MGI:7311644
Gene symbol: Shh
Gene name: sonic hedgehog
Probe: Shh probe215
Probe preparation: labelled with digoxigenin
Visualized with: Alkaline phosphatase
Results
Specimen 2D: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: upper jaw molar Present Regionally restricted 2D Expression in first molar tooth germ.
Specimen 2E: embryonic day 16.5; Msx1tm1Rilm/Msx1tm1Rilm (more )
Structure Level Pattern Image Note
TS24: upper jaw molar Absent 2E No expression in first molar tooth germ.
Specimen 2F: embryonic day 16.5; Msx1tm1Rilm/Msx1tm1Rilm, Sostdc1tm1Krum/Sostdc1tm1Krum (more )
Structure Level Pattern Image Note
TS24: upper jaw molar Present Regionally restricted 2F Expression in first molar tooth germ.
Specimen 3A (upper): embryonic day 14.25 (more )
Structure Level Pattern Image Note
TS22: primary enamel knot Present 3A (upper)
Specimen 3B (upper): embryonic day 14.25; Msx1tm1Rilm/Msx1tm1Rilm (more )
Structure Level Pattern Image Note
TS22: upper jaw molar Ambiguous 3B (upper) Expression markedly downregulated in maxillary molars.
Specimen 3C (upper): embryonic day 14.25; Msx1tm1Rilm/Msx1tm1Rilm, Sostdc1tm1Krum/Sostdc1tm1Krum (more )
Structure Level Pattern Image Note
TS22: upper jaw molar Present 3C (upper) Expression considerably restored only in maxillary molars.
Specimen 3A (lower): embryonic day 14.25 (more )
Structure Level Pattern Image Note
TS22: primary enamel knot Present 3A (lower)
Specimen 3B (lower): embryonic day 14.25; Msx1tm1Rilm/Msx1tm1Rilm (more )
Structure Level Pattern Image Note
TS22: lower jaw molar Ambiguous 3B (lower) Expression markedly downregulated in maxillary molars.
Specimen 3C (lower): embryonic day 14.25; Msx1tm1Rilm/Msx1tm1Rilm, Sostdc1tm1Krum/Sostdc1tm1Krum (more )
Structure Level Pattern Image Note
TS22: lower jaw molar Trace 3C (lower)
Specimen 4E (upper): embryonic day 14.25 (more )
Structure Level Pattern Image Note
TS22: upper jaw molar Present 4E (upper)
Specimen 4F (upper): embryonic day 14.25; Msx1tm1Rilm/Msx1tm1Rilm (more )
Structure Level Pattern Image Note
TS22: upper jaw molar Absent 4F (upper)
Specimen 4G (upper): embryonic day 14.25; Dkk2tm1Dwu/Dkk2tm1Dwu, Msx1tm1Rilm/Msx1tm1Rilm (more )
Structure Level Pattern Image Note
TS22: upper jaw molar Trace 4G (upper) Expression restored in maxillary molar.
Specimen 4E (lower): embryonic day 14.25 (more )
Structure Level Pattern Image Note
TS22: lower jaw molar Present 4E (lower)
Specimen 4F (lower): embryonic day 14.25; Msx1tm1Rilm/Msx1tm1Rilm (more )
Structure Level Pattern Image Note
TS22: lower jaw molar Absent 4F (lower)
Specimen 4G (lower): embryonic day 14.25; Dkk2tm1Dwu/Dkk2tm1Dwu, Msx1tm1Rilm/Msx1tm1Rilm (more )
Structure Level Pattern Image Note
TS22: lower jaw molar Absent 4G (lower)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory