Tg(tetO-SIX1)#Hlf
Transgene Detail
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| Symbol: |
Tg(tetO-SIX1)#Hlf |
| Name: |
transgene insertion, Heide L Ford |
| MGI ID: |
MGI:5795965 |
| Synonyms: |
TetSix |
| Transgene: |
Tg(tetO-SIX1)#Hlf Location: unknown
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| Alliance: |
Tg(tetO-SIX1)#Hlf page
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| Strain of Origin: |
Not Specified
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| Transgene Type: |
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Transgenic (Humanized sequence, Inducible, Inserted expressed sequence) |
| Inducer: |
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doxycycline/tetracycline |
| Mutation: |
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Insertion
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Tg(tetO-SIX1)#Hlf expresses
1 gene
Transgene expresses:
| Organism |
Expressed Gene |
Homolog in Mouse |
Note |
| human |
SIX1 (6495) |
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Mutation details: This transgene has an HA-tagged human SIX1 under the control of a tet operator. Four lines went germline (4910, 4922, 6239, and 6245). Lines 6239 and 4922 were the two showing the highest expression of the four with 6239 being the highest. The # designation is for cases where the founder line is unspecified or where data are pooled from muliple lines.
(J:152693)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:152693 McCoy EL, et al., Six1 expands the mouse mammary epithelial stem/progenitor cell pool and induces mammary tumors that undergo epithelial-mesenchymal transition. J Clin Invest. 2009 Sep;119(9):2663-77 |
| All: |
3 reference(s) |
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Analysis Tools
