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Gene Expression Data
Assay Details
Assay
Reference: J:124170 Fischer T, et al., Distinct but redundant expression of the Frizzled Wnt receptor genes at signaling centers of the developing mouse brain. Neuroscience. 2007 Jul 13;147(3):693-711
Assay type: RNA in situ
MGI Accession ID: MGI:7294204
Gene symbol: Fzd10
Gene name: frizzled class receptor 10
Probe: Fzd10 cDNA5
Probe preparation: Antisense labelled with S35 RNA
Results
Specimen 1J: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: future hindbrain Strong Regionally restricted 1J Expression is dorsal.
TS15: future midbrain Strong Regionally restricted 1J Expression is dorsal.
TS15: diencephalon Strong Regionally restricted 1J Expression is dorsal with a sharp anterior border of expression at the dorsal telencephalic/diencephalic boundary.
TS15: head mesenchyme Present Regionally restricted 1J Expression is in the head mesenchyme underlying the rostral telencephalon.

Specimen 2J: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: hindbrain Present Regionally restricted 2J Expression is dorsal.
TS17: midbrain Present Regionally restricted 2J Expression is dorsal.
TS17: diencephalon Present Regionally restricted 2J Expression is dorsal with a sharp anterior border of expression at the dorsal telencephalic/diencephalic boundary.
TS17: head mesenchyme Trace Regionally restricted 2J Expression is in the head mesenchyme underlying the rostral telencephalon.

Specimen 3J: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: metencephalon Strong Regionally restricted 3J Expression is dorsal.
TS20: thalamus Strong Regionally restricted 3J Expression is dorsal.
TS20: cerebellum primordium Strong 3J
TS20: cortical hem Strong 3J
TS20: midbrain-hindbrain junction Strong 3J
TS20: midbrain roof plate Strong Regionally restricted 3J Expression is in the tectum.
TS20: diencephalon Strong Regionally restricted 3J Expression is dorsal. Expression is lower in the subthalamic area, and a much weaker along the cephalic flexure.
TS20: midbrain Present Regionally restricted 3J Expression is along the cephalic flexure with a gap in expression in the caudal cephalic flexure abutting the midbrain/hindbrain boundary.
TS20: hindbrain Present Regionally restricted 3J Expression is ventral.

Specimen 4H: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: midbrain-hindbrain junction Strong 4H
TS17: hindbrain Strong Regionally restricted 4H Expression is dorsal.
TS17: midbrain Strong Regionally restricted 4H Expression is dorsal.

Specimen 4H': embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: midbrain Present Regionally restricted 4H' Expression is dorsal. there is weak expression throughout the neuroepithelium of the basal plate, across the alar/basal boundary and in the ventral part of the alar plate with stronger expression in two lateral stripes within the basal plate (abutting the floor plate), and in the dorsal part of the alar plate.
TS17: midbrain roof plate Present 4H'
TS17: midbrain floor plate Absent 4H'

Specimen 6I: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: hindbrain Strong Non-Uniform 6I Expression is weaker in the ventral anterior hindbrain.
TS20: midbrain Strong Non-Uniform 6I Expression is weaker in the cephalic flexure. There is a gap in expression along the anterior/posterior axis of the caudal cephalic flexure.

Specimen 6I': embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: midbrain lateral wall Strong Regionally restricted 6I' Expression is dorsal. Highest expression is in the ventricular zone and lower expression in the subventricular zone and marginal zone of the dorsal alar plate.
TS20: midbrain ventricular layer Strong Regionally restricted 6I' Expression is in the dorsal alar plate.
TS20: midbrain marginal layer Present Regionally restricted 6I' Expression is in the dorsal alar plate.
TS20: midbrain roof plate Strong Regionally restricted 6I'
TS20: midbrain floor plate Absent 6I'

Specimen 8J: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: telencephalon Strong Regionally restricted 8J Expression is dorsomedial. Absent in the dorsal and lateral pallium and the subpallium.
TS20: midbrain Strong Regionally restricted 8J Expression is dorsal.
TS20: thalamus Strong Regionally restricted 8J Expression is in the dorsal thalamus.
TS20: head mesenchyme Strong Regionally restricted 8J Expression is in the mesenchymal cells within the medial wall of the telencephalon.
TS20: cortical hem Present 8J
TS20: choroid plexus Absent 8J


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory