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Vipem1(icre)Smoc
Endonuclease-mediated Allele Detail
Summary
Symbol: Vipem1(icre)Smoc
Name: vasoactive intestinal polypeptide; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
MGI ID: MGI:7293133
Synonyms: Vipem1(IRES-iCre-SV40-pA)Smoc
Gene: Vip  Location: Chr10:5589218-5597617 bp, + strand  Genetic Position: Chr10, 1.97 cM, cytoband A1
Alliance: Vipem1(icre)Smoc page
Mutation
origin
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Endonuclease-mediated (Recombinase)
Mutation:    Insertion
 
Vipem1(icre)Smoc expression driven by 1 gene
 
Mutation detailsA IRES-iCre expression cassette was knocked into the Vip gene stop codon site. Vip encodes vasoactive intestinal polypeptide. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing Cre. This strain is useful for studying bronchiectasis, immunomodulatory and anti-inflammatory. (J:238766)
Inheritance:    Not Specified
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Vip (mouse)
Summary of all recombinase alleles driven by Vip.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Vip Mutation:  22 strains or lines available
References
Original:  J:238766 Shanghai Model Organisms Center, Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China. MGI Direct Data Submission. 2017;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory