Summary | Mutation origin | Mutation description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Pdynem2(icre)Smoc
Name:	prodynorphin; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
MGI ID:	MGI:7291601
Synonyms:	Pdynem1(IRES-iCre)Smoc
Gene:	Pdyn  Location: Chr2:129528485-129541764 bp, - strand  Genetic Position: Chr2, 63.19 cM
Alliance:	Pdynem2(icre)Smoc page

Strain of Origin:

C57BL/6J

Allele Type:    Endonuclease-mediated (Recombinase) Mutation:    Insertion   Pdynem2(icre)Smoc expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Pdyn (MGI:97535)   Mutation details: A IRES-iCre expression cassette was knocked into the Pdyn gene stop codon site. Pdyn encodes prodynorphin. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing cre. This strain may be useful for studying depression, stress, anxiety, pain response, circadian rhythm and appetite control. (J:238766) Inheritance:    Not Specified

Activity:	Tissue activity of this recombinase allele
Driver:	Pdyn (mouse) Summary of all recombinase alleles driven by Pdyn. Alliance mouse Pdyn gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pdyn Mutation:	19 strains or lines available

Original:	J:238766 Shanghai Model Organisms Center, Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China. MGI Direct Data Submission. 2017;
All:	1 reference(s)