Tg(RP23-247I11*)deltaHS4Jmbo
Transgene Detail
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| Symbol: |
Tg(RP23-247I11*)deltaHS4Jmbo |
| Name: |
transgene insertion deltaHS4, Joan M Boyes |
| MGI ID: |
MGI:7287427 |
| Synonyms: |
deltaHS4 |
| Transgene: |
Tg(RP23-247I11*)deltaHS4Jmbo Location: unknown
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| Alliance: |
Tg(RP23-247I11*)deltaHS4Jmbo page
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| Strain of Origin: |
Not Applicable
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| Transgene Type: |
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Transgenic (Epitope tag, Inserted expressed sequence) |
| Mutation: |
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Insertion
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Mutation details: The transgene insert consists of a segment of mouse BAC RP23-247I11 that contains the 3' half of the immunoglobulin lambda locus (from upstream of the Iglv1 promoter to 3 kb downstream of DNAse 1 hypersensitive site HS4, which is located ~40 kb downstream of the Iglj1/Iglc1 cluster). Sequence (39 bp) coding for a cMyc tag was inserted into an XhoI restriction site in the Iglc1 cluster. Further, DNAse 1 hypersensitive site HS4 was deleted (372 bp).
(J:320616)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:320616 Haque SF, et al., The Elambda(3-1) enhancer is essential for V(D)J recombination of the murine immunoglobulin lambda light chain locus. Biochem Biophys Res Commun. 2013 Nov 15;441(2):482-7 |
| All: |
1 reference(s) |
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Analysis Tools
