About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:304533 Levy I, et al., A phosphodiesterase 11 (Pde11a) knockout mouse expressed functional but reduced Pde11a: Phenotype and impact on adrenocortical function. Mol Cell Endocrinol. 2021 Jan 15;520:111071
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7286451
Gene symbol: Pde11a
Gene name: phosphodiesterase 11A
Antibody: anti-Pde11a (ab14624)
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen 1B: postnatal (more )
Structure Level Pattern Image Note
TS28: adrenal cortex Weak 1B
TS28: adrenal medulla Trace 1B
Specimen Suppl Table 1: postnatal adult (more )
Structure Cell Type Level Pattern Image Note
TS28: gray matter neuron Strong
TS28: cerebellum Purkinje cell layer Strong
TS28: small intestine epithelium Strong
TS28: spermatogonium Strong
TS28: urethra epithelium Strong
TS28: cranial ganglion Strong Regionally restricted Expression varied from strong to absent.
TS28: epididymis Strong Regionally restricted Expression varied from strong to absent.
TS28: myometrium Strong Regionally restricted Expression varied from strong to absent.
TS28: CA1 pyramidal cell layer Moderate
TS28: bronchiole Moderate
TS28: choroid plexus Moderate
TS28: dorsal root ganglion Moderate
TS28: trigeminal ganglion Moderate
TS28: dental pulp Moderate
TS28: dentin Moderate
TS28: enamel Moderate
TS28: glomerular tuft Moderate
TS28: pancreatic acinus Moderate
TS28: renal distal tubule Moderate
TS28: renal proximal tubule Moderate
TS28: stomach glandular region Moderate
TS28: sublingual gland Moderate
TS28: submandibular gland Moderate
TS28: tooth ameloblast Moderate
TS28: tooth odontoblast Moderate
TS28: thyroid gland thyroid follicular cell Moderate
TS28: cerebral cortex Moderate Regionally restricted Expression varied from moderate to absent.
TS28: CA2 pyramidal cell layer Weak
TS28: CA3 pyramidal cell layer Weak
TS28: adenohypophysis Weak
TS28: adrenal cortex Weak
TS28: adrenal medulla Weak
TS28: dentate gyrus granule cell layer Weak
TS28: dermis adipose tissue Weak
TS28: endometrium glandular epithelium Weak
TS28: endometrium luminal epithelium Weak
TS28: esophagus squamous epithelium Weak
TS28: hypothalamus Weak
TS28: inner renal medulla Weak
TS28: lacrimal gland Weak
TS28: large intestine epithelium Weak
TS28: loop of Henle Weak
TS28: myocardium layer Weak
TS28: outer renal medulla Weak
TS28: ovary stratum granulosum Weak
TS28: parotid gland Weak
TS28: retina ganglion cell layer Weak
TS28: thalamus Weak
TS28: thymus medullary core Weak
TS28: stomach Weak Regionally restricted Expression is weak in the non-glandular region and moderate in the glandular region.
TS28: liver hepatocyte Weak
TS28: large intestine Weak Regionally restricted Weak in epithelial cells and absent in tubular-, intestinal-, and sub-mucosal glands.
TS28: bone marrow Weak Regionally restricted Expression ranged from weak to absent.
TS28: gray matter astrocyte Absent
TS28: gray matter microglial cell Absent
TS28: circumventricular organ ependymal cell Absent
TS28: adenohypophysis pars intermedia Absent
TS28: alveolar duct Absent
TS28: alveolar sac Absent
TS28: aorta Absent
TS28: bone Absent
TS28: capillary Absent
TS28: cartilage Absent
TS28: cerebellum granule cell layer Absent
TS28: cornea Absent
TS28: coronary artery Absent
TS28: corpus luteum Absent
TS28: dermis Absent
TS28: endocardial lining Absent
TS28: endometrium stroma Absent
TS28: epidermis Absent
TS28: germ cell of ovary Absent
TS28: heart valve Absent
TS28: hippocampus molecular layer Absent
TS28: hypodermis Absent
TS28: interstitium of the testis Absent
TS28: islets of Langerhans Absent
TS28: lens Absent
TS28: lymph node cortex Absent
TS28: lymph node medulla Absent
TS28: mesenchymal stroma of ovary Absent
TS28: neurohypophysis Absent
TS28: ovary theca Absent
TS28: prostate gland Absent
TS28: seminiferous tubule Absent
TS28: thymus cortex Absent
TS28: venule Absent
TS28: visceral pericardium Absent
TS28: Sertoli cell Sertoli cell Absent
TS28: peripheral nervous system Schwann cell Absent
TS28: bronchiole epithelium basal cell Absent
TS28: bronchiole epithelium basal cell of epithelium of lobular bronchiole Absent
TS28: bronchiole epithelium intermediate epitheliocyte Absent
TS28: small intestine epithelium goblet cell Absent
TS28: white matter oligodendrocyte Absent
TS28: cranial ganglion glial cell Absent
TS28: retina layer retinal bipolar neuron Absent
Specimen S2 B: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: tympanic ring Present S2B
Specimen S2 C: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: tympanic ring Present S2C
Specimen S2 D: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: tympanic ring Present S2D
Specimen S2 Table Adult: postnatal adult (more )
Structure Level Pattern Image Note
TS28: small intestine Strong
TS28: choroid plexus Present
TS28: dorsal root ganglion Present
TS28: hippocampus Present
TS28: metanephros Present
TS28: adrenal gland Weak
TS28: cerebral cortex Weak
TS28: liver Weak
TS28: pancreas Weak
TS28: pituitary gland Weak
TS28: tooth Weak
TS28: chondrocranium Absent
TS28: hair Absent
TS28: tympanic ring Absent
Specimen S2 Table P1: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: small intestine Strong
TS27: choroid plexus Present
TS27: hair Present
TS27: cerebral cortex Weak
TS27: chondrocranium Weak
TS27: dorsal root ganglion Weak
TS27: hippocampus Weak
TS27: liver Weak
TS27: metanephros Weak
TS27: tooth Weak
TS27: tympanic ring Weak
TS27: pancreas Trace
TS27: adrenal gland Absent
TS27: pituitary gland Absent
Specimen S2 Table E15.5: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: chondrocranium Strong
TS23: tympanic ring Strong
TS23: choroid plexus Present
TS23: small intestine Present
TS23: tooth Present
TS23: hippocampus Ambiguous There is a discrepancy between the text and the table. Text states expression is present and the table indicates expression is absent.
TS23: dorsal root ganglion Weak
TS23: hair Weak
TS23: liver Weak
TS23: adrenal gland Absent
TS23: cerebral cortex Absent
TS23: metanephros Absent
TS23: pancreas Absent
TS23: pituitary gland Absent
Specimen S2 Table E14.5: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: tympanic ring Strong
TS22: chondrocranium Present
TS22: small intestine Present
TS22: hippocampus Ambiguous There is a discrepancy between the text and the table. Text states expression is present and the table indicates expression is absent.
TS22: choroid plexus Weak
TS22: hair Weak
TS22: liver Weak
TS22: tooth Weak
TS22: adrenal gland Absent
TS22: cerebral cortex Absent
TS22: dorsal root ganglion Absent
TS22: metanephros Absent
TS22: pancreas Absent
TS22: pituitary gland Absent
Specimen S2 Table E12.5: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: small intestine Present
Specimen S2 Table E9.5: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: embryo Absent
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory