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Gene Expression Data
Assay Details
Assay
Reference: J:323825 Giffen KP, et al., Mutation of SLC7A14 causes auditory neuropathy and retinitis pigmentosa mediated by lysosomal dysfunction. Sci Adv. 2022 Apr 8;8(14):eabk0942
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7284187
Gene symbol: Map1lc3b
Gene name: microtubule-associated protein 1 light chain 3 beta
Antibody: Anti-LC3B (D11) #3868
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen 8G wild type: postnatal month 3 (more )
Note: Double labeled: magenta - Map1lc3b; green - F-actin.
Structure Cell Type Level Pattern Image Note
TS28: cochlea cochlear inner hair cell Present Punctate 8G wild type (3 months)
Specimen 8G Knock-in: postnatal month 2; Slc7a14em1Jin/Slc7a14em1Jin (more )
Note: Double labeled: magenta - Map1lc3b; green - F-actin.
Structure Cell Type Level Pattern Image Note
TS28: cochlea cochlear inner hair cell Present Punctate 8G knock-in (2 months) The number of LC3 puncta in inner hair cells was significantly higher in the knock-in mice.
Specimen 8G Knockout: postnatal month 3; Slc7a14em1Jqu/Slc7a14em1Jqu (more )
Note: Double labeled: magenta - Map1lc3b; green - F-actin.
Structure Cell Type Level Pattern Image Note
TS28: cochlea cochlear inner hair cell Present Punctate 8G knockout (3 months) The number of LC3 puncta in inner hair cells was significantly higher in the knockout mice.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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