Summary | Mutation origin | Mutation description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Oxtrem2(icre)Yinn
Name:	oxytocin receptor; endonuclease-mediated mutation 2, Yukiko U Inoue
MGI ID:	MGI:7282234
Synonyms:	Oxtr1xPA-iCre, Oxtrem1(icre)Inot, Oxtr-T2A-iCre
Gene:	Oxtr  Location: Chr6:112450644-112466904 bp, - strand  Genetic Position: Chr6, 52.27 cM, cytoband E3
Alliance:	Oxtrem2(icre)Yinn page

Strain of Origin:

(C57BL/6 x C3H)F1

Allele Type:    Endonuclease-mediated (Epitope tag, Recombinase) Mutation:    Insertion   Oxtrem2(icre)Yinn expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Oxtr (MGI:109147)   Mutation details: Using CRISPR/cas9 technology, a 1xPA-tag and a T2A-iCre expression cassette were inserted into the Oxtr gene just upstream of the stop codon. (J:314171)

Activity:	Tissue activity of this recombinase allele
Driver:	Oxtr (mouse) Summary of all recombinase alleles driven by Oxtr. Comparative matrix view of recombinase activities Alliance mouse Oxtr gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Oxtr Mutation:	40 strains or lines available

Original:	J:314171 Inoue YU, et al., An Optimized Preparation Method for Long ssDNA Donors to Facilitate Quick Knock-In Mouse Generation. 7 new recombinases (including the one already entered), and 5 different reporter alleles. Cells. 2021 Apr 30;10(5)
All:	2 reference(s)