Summary | Mutation origin | Mutation description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Eomesem1(icre)Mhos
Name:	eomesodermin; endonuclease-mediated mutation 1, Mikio Hoshino
MGI ID:	MGI:7282233
Synonyms:	Eomesem1(icre)Inot, Tbr2-T2A-iCre
Gene:	Eomes  Location: Chr9:118307259-118315176 bp, + strand  Genetic Position: Chr9, 70.21 cM, cytoband F3
Alliance:	Eomesem1(icre)Mhos page

Strain of Origin:

Not Specified

Allele Type:    Endonuclease-mediated (Recombinase) Mutation:    Insertion   Eomesem1(icre)Mhos expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Eomes (MGI:1201683)   Mutation details: Using CRISPR/cas9 technology, a T2A-iCre expression cassette was inserted into Eomes (Tbr2) gene just upstream of the stop codon. (J:314171)

Activity:	Tissue activity of this recombinase allele
Driver:	Eomes (mouse) Summary of all recombinase alleles driven by Eomes. Alliance mouse Eomes gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Eomes Mutation:	41 strains or lines available

Original:	J:314171 Inoue YU, et al., An Optimized Preparation Method for Long ssDNA Donors to Facilitate Quick Knock-In Mouse Generation. 7 new recombinases (including the one already entered), and 5 different reporter alleles. Cells. 2021 Apr 30;10(5)
All:	1 reference(s)