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Gene Expression Data
Assay Details
Assay
Reference: J:240146 Lee B, et al., Single-stranded DNA binding proteins are required for LIM complexes to induce transcriptionally active chromatin and specify spinal neuronal identities. Development. 2016 May 15;143(10):1721-31
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7282181
Gene symbol: Isl1
Gene name: ISL1 transcription factor, LIM/homeodomain
Antibody: Anti-Isl1
Results
Specimen S3B +/+: embryonic day 11.5 (more )
Structure Cell Type Level Pattern Image Note
TS19: future spinal cord dorsal horn interneuron Present Regionally restricted S3B left Expressed in the ventral motor neurons and the dorsal interneurons.
TS19: future spinal cord motor neuron Present Regionally restricted S3B left Expressed in the ventral motor neurons and the dorsal interneurons.
Specimen S3B Ssdp2-/-: embryonic day 11.5; Ssbp2tm1Skyl/Ssbp2tm1Skyl (more )
Structure Cell Type Level Pattern Image Note
TS19: future spinal cord dorsal horn interneuron Present Regionally restricted S3B middle Reduced expression in both the ventral motor neurons and the dorsal interneurons.
TS19: future spinal cord motor neuron Present Regionally restricted S3B middle Reduced expression in both the ventral motor neurons and the dorsal interneurons.
Specimen S3B Ssdp1hsk/hsk: embryonic day 11.5; Ssbp3Tg(SOD1)1Hssk/Ssbp3Tg(SOD1)1Hssk (more )
Structure Cell Type Level Pattern Image Note
TS19: future spinal cord dorsal horn interneuron Present Regionally restricted S3B right Reduced expression in both the ventral motor neurons and the dorsal interneurons.
TS19: future spinal cord motor neuron Present Regionally restricted S3B right Reduced expression in both the ventral motor neurons and the dorsal interneurons.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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01/20/2026
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