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Gene Expression Data
Assay Details
Assay
Reference: J:95254 Grove M, et al., ABI2-deficient mice exhibit defective cell migration, aberrant dendritic spine morphogenesis, and deficits in learning and memory. Mol Cell Biol. 2004 Dec;24(24):10905-22
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7282029
Gene symbol: Abi2
Gene name: abl interactor 2
Antibody: anti-Abi 5421
Results
Specimen 4C1a/b: embryonic day 16.5; Abi2tm1Pen/Abi2tm1Pen (more )
Note: Double labeled: red - Abi2; green - Ctnnb1 (assay MGI:7282030).
Structure Level Pattern Image Note
TS24: lens fiber Strong Regionally restricted 4C1a , 4C1b Prominent expression at cell-cell borders of secondary lens fibers in anterior of lens. Expression colocalized or adjacent to Ctnnb1 expression.
Specimen 4C2a: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: lens Present Regionally restricted 4C2a Expression in double row of puncta at interface of secondary lens fibers and anterior epithelial cells at the epithelial cell-fiber interface (EFI).
Specimen 4C2b/d: embryonic day 16.5 (more )
Note: Double labeled: red - Abi2; green - Ctnnb1 (assay MGI:7282030).
Structure Level Pattern Image Note
TS24: lens fiber Present Regionally restricted 4C2d , 4C2b Co-localization with beta-catenin (Ctnnb1) along secondary lens fiber cell-cell borders.
Specimen 4C3: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: lens Present Regionally restricted 4C3 Expression in double row of puncta at interface of secondary lens fibers and anterior epithelial cells at the epithelial cell-fiber interface (EFI).
Specimen 4C4: embryonic day 16.5 (more )
Note: Double labeled: red - Abi2; green - Ctnnb1 (assay MGI:7282030).
Structure Level Pattern Image Note
TS24: lens fiber Present Regionally restricted 4C4 Co-localization with beta-catenin (Ctnnb1) at tips of secondary lens fibers at epithelial cell-fiber interface (EFI).
Specimen 7A1/A3: embryonic day 16.5 (more )
Note: Double labeled: red - Abi2; green - Ctnnb1 (assay MGI:7282030).
Structure Level Pattern Image Note
TS24: cerebral cortex Strong Regionally restricted 7A3 , 7A1 Prominent expression along border of lateral ventricles. Expression colocalized with Ctnnb1 at cell-cell borders and along lateral ventricle.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory