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Gene Expression Data
Assay Details
Assay
Reference: J:95254 Grove M, et al., ABI2-deficient mice exhibit defective cell migration, aberrant dendritic spine morphogenesis, and deficits in learning and memory. Mol Cell Biol. 2004 Dec;24(24):10905-22
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7282028
Gene symbol: Abi2
Gene name: abl interactor 2
Antibody: anti-Abi 5421
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen 4B1: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: lens fiber Strong Regionally restricted 4B1 High levels of expression at tips of migrating secondary lens fiber, particularly at transition zone.

Specimen 4B2: embryonic day 18.5; Abi2tm1Pen/Abi2tm1Pen (more )
Structure Level Pattern Image Note
TS26: lens Absent 4B2

Specimen 4B3: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: lens Strong Regionally restricted 4B3 Prominent expression at base of newly differentiating secondary lens fiber and anterior epithelial cells.

Specimen 7B1: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: cerebral cortex marginal zone Strong 7B1 Prominent expression in marginal zone.

Specimen 7B2: embryonic day 18.5; Abi2tm1Pen/Abi2tm1Pen (more )
Structure Level Pattern Image Note
TS26: cerebral cortex Absent 7B2

Specimen 7B3: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: cerebral cortex marginal zone Present Regionally restricted 7B3 Expression in cell body and horizontal process of Cajal Retzius-like cells in marginal zone.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory