Gene Expression Data
Assay Details
Assay
|
Reference:
|
J:95254
Grove M, et al., ABI2-deficient mice exhibit defective cell migration, aberrant dendritic spine morphogenesis, and deficits in learning and memory. Mol Cell Biol. 2004 Dec;24(24):10905-22
|
Assay type:
|
Immunohistochemistry
|
MGI Accession ID:
|
MGI:7282028
|
Gene symbol:
|
Abi2
|
Gene name:
|
abl interactor 2
|
Antibody:
|
anti-Abi 5421
|
Detection system:
|
Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
|
|
Results
|
Specimen
4B1:
embryonic day 18.5
(more )
Specimen
4B1:
(close )
Genetic Background:
|
C57BL/6
|
Age:
|
embryonic day 18.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS26: lens fiber |
Strong |
Regionally restricted |
4B1
|
High levels of expression at tips of migrating secondary lens fiber, particularly at transition zone.
|
Specimen
4B2:
(close )
Genetic Background:
|
B6.Cg-Abi2tm1Pen
|
Mutant Allele(s):
|
Abi2tm1Pen/Abi2tm1Pen
|
Age:
|
embryonic day 18.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS26: lens |
Absent |
|
4B2
|
|
Specimen
4B3:
embryonic day 18.5
(more )
Specimen
4B3:
(close )
Genetic Background:
|
C57BL/6
|
Age:
|
embryonic day 18.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS26: lens |
Strong |
Regionally restricted |
4B3
|
Prominent expression at base of newly differentiating secondary lens fiber and anterior epithelial cells.
|
Specimen
7B1:
embryonic day 18.5
(more )
Specimen
7B1:
(close )
Genetic Background:
|
C57BL/6
|
Age:
|
embryonic day 18.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Specimen
7B2:
(close )
Genetic Background:
|
B6.Cg-Abi2tm1Pen
|
Mutant Allele(s):
|
Abi2tm1Pen/Abi2tm1Pen
|
Age:
|
embryonic day 18.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Specimen
7B3:
embryonic day 18.5
(more )
Specimen
7B3:
(close )
Genetic Background:
|
C57BL/6
|
Age:
|
embryonic day 18.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS26: cerebral cortex marginal zone |
Present |
Regionally restricted |
7B3
|
Expression in cell body and horizontal process of Cajal Retzius-like cells in marginal zone.
|
|