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Gene Expression Data
Assay Details
Assay
Reference: J:309566 Schlusche AK, et al., Developmental HCN channelopathy results in decreased neural progenitor proliferation and microcephaly in mice. Proc Natl Acad Sci U S A. 2021 Aug 31;118(35):e2009393118
Assay type: RT-PCR
MGI Accession ID: MGI:7281467
Gene symbol: Hcn4
Gene name: hyperpolarization-activated, cyclic nucleotide-gated K+ 4
Probe: Mm01176086_m1
Assay notes: Quantitative RT-PCR. Relative expression was normalized to Gapdh and expression level in same region at E13.
Results
Image: S1B Hcn4 ©

 Sample Information Bands Other Sample Information
Lane AgeStructure Size Not Specified Amount Genetic BackgroundMutant Allele(s)Sex Note
E13 E13.0 (a) TS21: allocortex Present (b) Not Specified Not Specified Not Specified Specimen was hippocampus.
E15 E15.0 (a) TS23: hippocampus Present (c) Not Specified Not Specified Not Specified
E18 E18.0 (a) TS26: hippocampus Present (d) Not Specified Not Specified Not Specified
P7 P7 TS28: hippocampus Present Not Specified Not Specified Not Specified
P35 P35 TS28: hippocampus Present Not Specified Not Specified Not Specified
Notes:
(a) Age of embryo at noon of plug day not specified in reference.
(b) Hcn4 was the second highest expressed transcript at E13.
(c) Expression peaked at E15. Expression level comparable to that of Hcn1 and Hcn2 at E15.
(d) Expression level comparable to that of Hcn1 and Hcn2 at E18.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory