Tg(Postn-icre/ERT2)#Wet
Transgene Detail
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Symbol: |
Tg(Postn-icre/ERT2)#Wet |
Name: |
transgene insertion, Nina Wettschureck |
MGI ID: |
MGI:7281316 |
Synonyms: |
PnCreERT2, Postn-iCre |
Transgene: |
Tg(Postn-icre/ERT2)#Wet Location: unknown
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Alliance: |
Tg(Postn-icre/ERT2)#Wet page
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Transgene Type: |
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Transgenic (Inducible, Recombinase) |
Inducer: |
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tamoxifen |
Mutation: |
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Insertion
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Tg(Postn-icre/ERT2)#Wet expression driven by
1 gene
Transgene expression driven by:
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Mutation details: A cassette consisting of the CreERT2 cDNA followed by a polyadenylation signal from bovine growth hormone was introduced after the start codon of the mouse Postn gene carried by BAC RP23-480C1 using Red E/T-mediated recombination. After homologous recombination and Flp-mediated excision of the ampicillin cassette, the construct was injected into oocytes of C57/BL6 mice. Five founder lines were generated and characterized. The pound symbol (#) is used when no line is specified and/or lines are pooled.
(J:254071)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Postn
(mouse)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Original: |
J:254071 Kaur H, et al., Targeted Ablation of Periostin-Expressing Activated Fibroblasts Prevents Adverse Cardiac Remodeling in Mice. Circ Res. 2016 Jun 10;118(12):1906-17 |
All: |
2 reference(s) |
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