Gene Expression Data
Assay Details
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Assay
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Reference:
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J:58562
Yamashita T, et al., Neurotrophin binding to the p75 receptor modulates Rho activity and axonal outgrowth. Neuron. 1999 Nov;24(3):585-93
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:7281140
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Gene symbol:
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Tubb3
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Gene name:
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tubulin, beta 3 class III
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Antibody:
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anti-TuJ1
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Detection system:
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Secondary antibody coupled to horseradish peroxidase
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Results
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Specimen
E11.0 wild-type:
embryonic day 11.0
(more  )
Note: 42 somites
Specimen
E11.0 wild-type:
(close  )
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Genetic Background:
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involves: 129S4/SvJae * BALB/c
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Age:
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embryonic day 11.0
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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Dent's Fixative
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Note:
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42 somites
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| Structure |
Level |
Pattern |
Image |
Note |
| TS18: spinal nerve |
Present |
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Authors report nerve growth rates identical to that of +/- embryos.
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Specimen
7A p75NTR+/-:
embryonic day 11.0; Ngfrtm1Jae/Ngfr +
(more )
Note: 42 somites
Specimen
7A p75NTR+/-:
(close )
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Genetic Background:
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involves: 129S4/SvJae * BALB/c
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Mutant Allele(s):
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Ngfrtm1Jae/Ngfr+
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Age:
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embryonic day 11.0
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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Dent's Fixative
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Note:
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42 somites
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Specimen
7A p75NTR-/-:
(close )
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Genetic Background:
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involves: 129S4/SvJae * BALB/c
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Mutant Allele(s):
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Ngfrtm1Jae/Ngfrtm1Jae
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Age:
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embryonic day 11.0
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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Dent's Fixative
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Note:
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42 somites
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| Structure |
Level |
Pattern |
Image |
Note |
| TS18: spinal nerve |
Present |
Regionally restricted |
7A p75NTR-/-
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Outgrowth of thoracic intercostal nerves clearly retarded compared with +/- littermates.
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Specimen
E12.0 wild--type:
embryonic day 12.0
(more )
Note: 49 somites
Specimen
E12.0 wild--type:
(close )
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Genetic Background:
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involves: 129S4/SvJae * BALB/c
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Age:
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embryonic day 12.0
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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Dent's Fixative
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Note:
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49 somites
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: spinal nerve |
Present |
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Authors report nerve growth rates identical to that of +/- embryos.
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Specimen
7B p75NTR+/-:
embryonic day 12.0; Ngfrtm1Jae/Ngfr +
(more )
Note: 49 somites
Specimen
7B p75NTR+/-:
(close )
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Genetic Background:
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involves: 129S4/SvJae * BALB/c
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Mutant Allele(s):
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Ngfrtm1Jae/Ngfr+
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Age:
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embryonic day 12.0
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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Dent's Fixative
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Note:
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49 somites
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Specimen
7B p75NTR-/-:
(close )
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Genetic Background:
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involves: 129S4/SvJae * BALB/c
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Mutant Allele(s):
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Ngfrtm1Jae/Ngfrtm1Jae
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Age:
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embryonic day 12.0
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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Dent's Fixative
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Note:
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49 somites
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: spinal nerve |
Present |
Regionally restricted |
7B p75NTR-/-
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Outgrowth of thoracic intercostal nerves delayed compared with +/- littermates. Similar delay in innervation of superficial motor axons in forelimb.
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Analysis Tools
