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Tg(Zp3-EGFP,-RNAi:Ctcf)1Msb
Transgene Detail
Summary
Symbol: Tg(Zp3-EGFP,-RNAi:Ctcf)1Msb
Name: transgene insertion 1, Marisa Bartolomei
MGI ID: MGI:7281088
Transgene: Tg(Zp3-EGFP,-RNAi:Ctcf)1Msb  Location: unknown  
Alliance: Tg(Zp3-EGFP,-RNAi:Ctcf)1Msb page
Transgene
origin
Strain of Origin:  (C57BL/6J x SJL/J)F1
Transgene
description
Transgene Type:    Transgenic (Knockdown, Reporter)
Mutation:    Insertion
  Tg(Zp3-EGFP,-RNAi:Ctcf)1Msb involves 1 genes/genome features (Ctcf) View all
 
Mutation detailsThe promoter drives oocyte-specifiec expression of an EGFP reporter gene and a double strand RNA targeting Ctcf. Five lines were generated; lines 1 and 21 with very little CTCF mRNA while lines 4 and 56 exhibit a more modest decrease. Line 1 was selected as the representative line. (J:90538)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:90538 Fedoriw AM, et al., Transgenic RNAi reveals essential function for CTCF in H19 gene imprinting. Science. 2004 Jan 9;303(5655):238-40
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory