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Gene Expression Data
Assay Details
Assay
Reference: J:74216 Aigner A, et al., Immunolocalization of an FGF-binding protein reveals a widespread expression pattern during different stages of mouse embryo development. Histochem Cell Biol. 2002 Jan;117(1):1-11
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7281084
Gene symbol: Fgfbp1
Gene name: fibroblast growth factor binding protein 1
Antibody: FGF-BP antibody
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen 1a: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: oral region epithelium Strong 1a Expression in epithelia of oral cavity.
TS24: intestine epithelium Strong 1a
TS24: rectum epithelium Present Regionally restricted 1a Expression confined to distal part of rectum.
TS24: rectum lamina propria Absent 1a
TS24: rectum muscularis mucosa Absent 1a
TS24: liver Weak 1a
TS24: epidermis Strong Regionally restricted 1a Strong expression in squamous cells.
TS24: vibrissa follicle Strong 1a
TS24: olfactory epithelium Present 1a
TS24: central nervous system Trace 1a Only very faintly positive for expression.
TS24: axial skeleton Absent 1a No expression in spine.
TS24: aorta Weak Regionally restricted 1a Weak expression in aortic trunk.
TS24: cardiac muscle tissue Absent 1a
TS24: urothelium of bladder Weak 1a
TS24: clavicle Present 1a
TS24: bone marrow Absent 1a
TS24: thymus Strong 1a
TS24: brown fat Strong 1a

Specimen E16 not shown: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: tooth Strong Regionally restricted Expression in dental pulp, decreasing in intensity toward inner enamel epithelium.
TS24: outer enamel epithelium Present
TS24: inner enamel epithelium Present Regionally restricted Expression in apical side of adamantoblasts of inner enamel epithelium.
TS24: renal tubule Strong
TS24: maturing glomerular tuft Weak
TS24: renal interstitium Present

Specimen 2a left: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: oral region epithelium Moderate 2a left
TS22: submandibular gland primordium epithelium Strong Regionally restricted 2a left Strong expression in epithelial cells of acini.
TS22: intestine epithelium Strong 2a left
TS22: liver Strong 2a left
TS22: epidermis Strong Regionally restricted 2a left Strong expression in squamous cells.
TS22: vibrissa follicle Strong 2a left
TS22: neocortex Present 2a left
TS22: olfactory epithelium Present 2a left
TS22: pituitary gland Present 2a left
TS22: axial skeleton Weak 2a left
TS22: cardiac muscle tissue Weak 2a left

Specimen 2a right: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: oral region epithelium Moderate 2a right
TS22: submandibular gland primordium epithelium Strong Regionally restricted 2a right Strong expression in epithelial cells of acini.
TS22: intestine epithelium Strong 2a right
TS22: liver Strong 2a right
TS22: epidermis Strong Regionally restricted 2a right Strong expression in squamous cells.
TS22: neocortex Present 2a right
TS22: olfactory epithelium Present 2a right
TS22: pituitary gland Present 2a right
TS22: axial skeleton Weak 2a right
TS22: cardiac muscle tissue Weak 2a right

Specimen 2b left: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: oral region epithelium Weak 2b left
TS20: liver Strong 2b left
TS20: epidermis Strong Regionally restricted 2b left Strong expression in squamous cells.
TS20: vibrissa follicle Strong 2b left
TS20: olfactory epithelium Present 2b left
TS20: medulla oblongata Present 2b left
TS20: midbrain roof plate Present 2b left
TS20: midbrain-hindbrain junction Present 2b left
TS20: axial skeleton Present 2b left Expression in spine.
TS20: dorsal root ganglion Strong 2b left
TS20: cardiac muscle tissue Weak 2b left
TS20: bone Present 2b left
TS20: cartilage Present 2b left

Specimen 2b right: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: oral region epithelium Weak 2b right
TS20: liver Strong 2b right
TS20: epidermis Strong Regionally restricted 2b right Strong expression in squamous cells.
TS20: vibrissa follicle Strong 2b right
TS20: olfactory epithelium Present 2b right
TS20: medulla oblongata Present 2b right
TS20: midbrain roof plate Present 2b right
TS20: midbrain-hindbrain junction Present 2b right
TS20: axial skeleton Present 2b right Expression in spine.
TS20: dorsal root ganglion Strong 2b right
TS20: cardiac muscle tissue Weak 2b right
TS20: bone Present 2b right
TS20: cartilage Present 2b right

Specimen 2c left: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: oral region epithelium Weak 2c left
TS16: olfactory epithelium Present 2c left
TS16: dorsal root ganglion Strong 2c left
TS16: neural tube Strong 2c left
TS16: chorioallantoic placenta Present 2c left

Specimen 2c right: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: oral region epithelium Weak 2c right
TS16: olfactory epithelium Present 2c right
TS16: dorsal root ganglion Strong 2c right
TS16: neural tube Strong 2c right
TS16: chorioallantoic placenta Present 2c right

Specimen 2d: embryonic day 8.0 (more )
Structure Level Pattern Image Note
TS12: embryo Weak Widespread 2d Widespread distribution of expression in several though not all tissues.

Specimen 3a: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: tongue epithelium Strong Regionally restricted 3a Strong expression in stratified squamous epithelium.
TS24: tongue muscle Weak Regionally restricted 3a Weaker expression in striated muscle.

Specimen 3b: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: submandibular gland primordium epithelium Strong Regionally restricted 3b Strong expression in epithelial cells of acini.

Specimen 3c: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: duodenum epithelium Present 3c
TS24: duodenum lamina propria Absent 3c
TS24: duodenum muscularis mucosa Absent 3c
TS24: liver Weak 3c

Specimen 3d: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: liver Strong 3d

Specimen 3e: embryonic day 16.0 (more )
Structure Cell Type Level Pattern Image Note
TS24: liver hepatocyte Present 3e

Specimen 3f: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: pancreatic acinus Present 3f
TS24: pancreatic duct Present Regionally restricted 3f Expresssion in epithelia of pancreatic ducts.

Specimen 3g: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: trachea epithelium Present 3g

Specimen 3h: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: bronchus epithelium Strong 3h Strong expression in epithelium of rudimentary bronchial structure.

Specimen 3i: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: choroid plexus Moderate 3i
TS24: pituitary gland Moderate 3i

Specimen 3j: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: midbrain roof plate Present 3j
TS24: midbrain Present Regionally restricted 3j No expression in ventral part of midbrain.

Specimen 3k: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: thymus Present Regionally restricted 3k Expression confined to cortex. Only sporadic expressing cells in medulla.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory