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Gene Expression Data
Assay Details
Assay
Reference: J:181888 Ashe A, et al., Mutations in mouse Ift144 model the craniofacial, limb and rib defects in skeletal ciliopathies. Hum Mol Genet. 2012 Apr 15;21(8):1808-23
Assay type: RNA in situ
MGI Accession ID: MGI:7279176
Gene symbol: Ptch1
Gene name: patched 1
Probe: Ptch cDNA1
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 2G: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: embryo Present Regionally restricted 2G
TS17: forelimb bud Present 2G
Specimen 2H: embryonic day 10.5; Wdr19twto/Wdr19twto (more )
Structure Level Pattern Image Note
TS17: embryo Present Regionally restricted 2H Authors report a general increase in or ectopic expression compared with control.
TS17: 1st branchial arch mandibular component Present 2H Increased or ectopic expression particularly in facial prominences and limb.
TS17: forelimb bud Present 2H Increased or ectopic expression particularly in facial prominences and limb.
Specimen 2I: embryonic day 10.5; Wdr19dmhd/Wdr19twto (more )
Structure Level Pattern Image Note
TS17: embryo Present Regionally restricted 2I Authors report a general increase in or ectopic expression compared with control.
TS17: 1st branchial arch mandibular component Present 2I Increased expression in facial prominences more marked in dmhd/twt and dmhd embryos.
TS17: 1st branchial arch maxillary component Present 2I Increased expression in facial prominences more marked in dmhd/twt and dmhd embryos.
TS17: forelimb bud Present 2I
TS17: trunk mesenchyme Present Regionally restricted 2I Evidence of upregulated Hh signalling in inter-limb flank region.
Specimen 2J: embryonic day 10.5; Wdr19dmhd/Wdr19dmhd (more )
Structure Level Pattern Image Note
TS17: embryo Present Regionally restricted 2J Authors report a general increase in or ectopic expression compared with control.
TS17: 1st branchial arch mandibular component Present 2J Increased expression in facial prominences more marked in dmhd/twt and dmhd embryos.
TS17: 1st branchial arch maxillary component Present 2J Increased expression in facial prominences more marked in dmhd/twt and dmhd embryos.
TS17: forelimb bud Present 2J
TS17: trunk mesenchyme Present Regionally restricted 2J Evidence of upregulated Hh signalling in inter-limb flank region.
Specimen 6F: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: forelimb bud Present Regionally restricted 6F Expression in posterior of limb bud.
Specimen 6G: embryonic day 10.5; Wdr19twto/Wdr19twto (more )
Structure Level Pattern Image Note
TS17: forelimb bud Present Regionally restricted 6G Expression expanded into anterior of forelimb compared with control.
Specimen 6H: embryonic day 10.5; Wdr19dmhd/Wdr19twto (more )
Structure Level Pattern Image Note
TS17: forelimb bud Present Regionally restricted 6H Expression expanded into anterior of forelimb compared with control.
Specimen 6I: embryonic day 10.5; Wdr19dmhd/Wdr19dmhd (more )
Structure Level Pattern Image Note
TS17: forelimb bud Present Regionally restricted 6I Expression expanded into anterior of forelimb compared with control.
Specimen S3A: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: forelimb bud Present Regionally restricted S3A Expression in posterior of limb bud.
Specimen S3B: embryonic day 11.5; Wdr19twto/Wdr19twto (more )
Structure Level Pattern Image Note
TS19: forelimb bud Present Regionally restricted S3B Expression expanded into anterior of forelimb compared with control
Specimen S3C: embryonic day 11.5; Wdr19dmhd/Wdr19twto (more )
Structure Level Pattern Image Note
TS19: forelimb bud Present Regionally restricted S3C Expression expanded into anterior of forelimb compared with control
Specimen S3D: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: hindlimb bud Present Regionally restricted S3D Expression in posterior of limb bud.
Specimen S3E: embryonic day 11.5; Wdr19twto/Wdr19twto (more )
Structure Level Pattern Image Note
TS19: hindlimb bud Present Regionally restricted S3E Expression expanded into anterior of hindlimb compared with control.
Specimen S3F: embryonic day 11.5; Wdr19dmhd/Wdr19twto (more )
Structure Level Pattern Image Note
TS19: hindlimb bud Present Regionally restricted S3F Expression expanded into anterior of hindlimb compared with control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/30/2025
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