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Gene Expression Data
Assay Details
Assay
Reference: J:311933 Kong JH, et al., Gene-teratogen interactions influence the penetrance of birth defects by altering Hedgehog signaling strength. Development. 2021 Oct 1;148(19):dev199867
Assay type: Western blot
MGI Accession ID: MGI:7279107
Gene symbol: Smo
Gene name: smoothened, frizzled class receptor
Antibody: anti-Smo
Results
Image: 2C SMO ©

 Sample Information Bands Other Sample Information
Lane AgeStructure Size Not Specified (a) Size Not Specified (b) Genetic BackgroundMutant Allele(s)Sex
Mosmo+/+ (Emb1) E12.5 TS20: embryo Weak Ambiguous involves: C57BL/6 Not Specified
Mosmo+/+ (Emb2) E12.5 TS20: embryo Weak Ambiguous involves: C57BL/6 Not Specified
Mosmo-/- (Emb1) E12.5 TS20: embryo Present (c) Strong (d) C57BL/6-Mosmoem1Rroh Mosmoem1Rroh/Mosmoem1RrohNot Specified
Mosmo-/- (Emb2) E12.5 TS20: embryo Present (c) Strong (d) C57BL/6-Mosmoem1Rroh Mosmoem1Rroh/Mosmoem1RrohNot Specified
Notes:
(a) SMO ER
(b) SMO post-ER
(c) Expression increased compared with control.
(d) Dramatic increase in expression of form transversing endoplamic reticulum
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory