Gene Expression Data
Assay Details
Assay
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Reference:
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J:56986
Post LC, et al., Altered Hox expression and increased cell death distinguish Hypodactyly from Hoxa13 null mice. Int J Dev Biol. 1999 Jul;43(4):287-94
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:7266637
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Gene symbol:
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Hoxa11
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Gene name:
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homeobox A11
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Probe:
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Hoxa11 probe13
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Probe preparation:
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Antisense labelled with digoxigenin RNA
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Results
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Specimen
3 +/+:
embryonic day 11.5
(more )
Specimen
3 +/+:
(close )
Genetic Background:
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Not Specified
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Age:
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embryonic day 11.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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Structure |
Level |
Pattern |
Image |
Note |
TS19: forelimb bud |
Present |
Regionally restricted |
3_Hoxa11 left
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Restricted to a narrow stripe corresponding to the autopod/zeugopod junction.
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Specimen
3 Hd/Hd:
(close )
Genetic Background:
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involves: C3HeB/FeJ * C57BL/6J
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Mutant Allele(s):
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Hoxa13Hd/Hoxa13Hd
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Age:
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embryonic day 11.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
|
Structure |
Level |
Pattern |
Image |
Note |
TS19: forelimb bud |
Present |
Regionally restricted |
3_Hoxa11 middle
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Expression abnormally remained as in most of the autopod except for a small area at the posterior distal tip.
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Specimen
3 -/-:
(close )
Genetic Background:
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either: (involves: 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6J)
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Mutant Allele(s):
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Hoxa13tm2Ipc/Hoxa13tm2Ipc
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Age:
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embryonic day 11.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
|
Structure |
Level |
Pattern |
Image |
Note |
TS19: forelimb bud |
Present |
Regionally restricted |
3_Hoxa11 right
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Expression abnormally remained as in most of the autopod except for a small area at the posterior distal tip.
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