About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:278471 Nakanishi H, et al., Tmc2 expression partially restores auditory function in a mouse model of DFNB7/B11 deafness caused by loss of Tmc1 function. Sci Rep. 2018 Aug 14;8(1):12125
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7266316
Gene symbol: Kcnq4
Gene name: potassium voltage-gated channel, subfamily Q, member 4
Antibody: anti-KCNQ4
Detection system: Secondary antibody coupled to Alexa Fluor 488
Assay notes: Two antibodies were described, but the one used in this assay was not detailed. Anti-KCNQ4 MGI:7266306 may have been used in this assay.
Results
Specimen 8A Tmc1 +/+: postnatal day 25 (more )
Note: Double labeled: green - Kcnq4; red - Pvalb (assay MGI:7266317).
Structure Cell Type Level Pattern Image Note
TS28: cochlea cochlear outer hair cell Present Regionally restricted 8A Tmc1 +/+ Expression around perimeter of outer hair cells in apical cohlear turn.
Specimen 8A Tmc1 delta/delta: postnatal day 25; Tmc1tm1.1Ajg/Tmc1tm1.1Ajg (more )
Note: Double labeled: green - Kcnq4; red - Pvalb (assay MGI:7266317).
Structure Level Pattern Image Note
TS28: cochlea Absent 8A Tmc1 delta/delta
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory