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Tg(Ins1-IFNB1)28Fbos
Transgene Detail
Summary
Symbol: Tg(Ins1-IFNB1)28Fbos
Name: transgene insertion 28, Fatima Bosch
MGI ID: MGI:7265048
Synonyms: TgIFN-beta-28
Transgene: Tg(Ins1-IFNB1)28Fbos  Location: unknown  
Alliance: Tg(Ins1-IFNB1)28Fbos page
Transgene
origin
Strain of Origin:  C57BL/6 x SJL
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Ins1-IFNB1)28Fbos expresses 1 gene
 
Mutation detailsA human IFNB1 cDNA expression is driven by a rat Ins1 promoter. Two founder mice were obtained. Lines 28 and 56 carried about 5 and 20 intact copies of the transgene, respectively, as analyzed by Southern blot. (J:47674)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:47674 Pelegrin M, et al., Evidence from transgenic mice that interferon-beta may be involved in the onset of diabetes mellitus. J Biol Chem. 1998 May 15;273(20):12332-40
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
09/30/2025
MGI 6.24
The Jackson Laboratory