Gene Expression Data
Assay Details
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Assay
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Reference:
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J:149571
MacKenzie B, et al., Twisted gastrulation limits apoptosis in the distal region of the mandibular arch in mice. Dev Biol. 2009 Apr 1;328(1):13-23
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Assay type:
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In situ reporter (knock in)
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MGI Accession ID:
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MGI:7264980
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Gene symbol:
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Twsg1
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Gene name:
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twisted gastrulation BMP signaling modulator 1
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Reporter:
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lacZ
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Direct Detection
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Assay notes:
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Fixation with 2% formaldehyde, 0.2% glutaraldehyde.
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Results
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Specimen
1B:
(close  )
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Genetic Background:
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involves: 129S6/SvEvTac * C57BL/6NTac
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Mutant Allele(s):
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Twsg1tm1Ecan/Twsg1+
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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Other - See Notes
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| Structure |
Level |
Pattern |
Image |
Note |
| TS15: 1st branchial arch |
Present |
Widespread |
1B
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Expression throughout mandibular arch, in both proximal and distal regions.
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Specimen
1D:
embryonic day 10.5; Twsg1tm1Ecan/Twsg1 +
(more  )
Specimen
1D:
(close )
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Genetic Background:
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involves: 129S6/SvEvTac * C57BL/6NTac
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Mutant Allele(s):
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Twsg1tm1Ecan/Twsg1+
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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Other - See Notes
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: 1st branchial arch |
Present |
Graded |
1D
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Slight gradient of expression, with prominance in distal region.
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Specimen
1F:
embryonic day 11.5; Twsg1tm1Ecan/Twsg1 +
(more )
Specimen
1F:
(close )
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Genetic Background:
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involves: 129S6/SvEvTac * C57BL/6NTac
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Mutant Allele(s):
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Twsg1tm1Ecan/Twsg1+
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Age:
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embryonic day 11.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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Other - See Notes
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| Structure |
Level |
Pattern |
Image |
Note |
| TS19: 1st branchial arch |
Present |
Regionally restricted |
1F
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Expression restricted toward oral epithelium and proximal arch.
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Analysis Tools
