Sox6tm1.1(cre)Awar
Targeted Allele Detail
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Symbol: |
Sox6tm1.1(cre)Awar |
Name: |
SRY (sex determining region Y)-box 6; targeted mutation 1.1, Rajeshwar Awatramani |
MGI ID: |
MGI:7264416 |
Synonyms: |
Sox6-Cre |
Gene: |
Sox6 Location: Chr7:115070107-115638031 bp, - strand Genetic Position: Chr7, 61.29 cM
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Alliance: |
Sox6tm1.1(cre)Awar page
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Germline Transmission: |
Earliest citation of germline transmission:
J:321252
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Parent Cell Line: |
PRX-B6N (ES Cell)
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Strain of Origin: |
C57BL/6NTac
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Allele Type: |
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Targeted (Recombinase) |
Mutation: |
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Insertion
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Sox6tm1.1(cre)Awar expression driven by
1 gene
Knock-in expression driven by:
Organism |
Driver Gene |
Note |
mouse |
Sox6 (MGI:98368) |
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Mutation details: By homologous recombination in ES cells, FRT-STOP-Puro-FRT cassette was inserted into the intronic region between exons 2 and 3 and a NLS-Cre-polyA was inserted into the Sox6 gene in-frame to the endogenous ATG. Flp-mediated recombination removed the STOP and selection cassette.
(J:321252)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Sox6
(mouse)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Sox6 Mutation: |
59 strains or lines available
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Original: |
J:321252 Pereira Luppi M, et al., Sox6 expression distinguishes dorsally and ventrally biased dopamine neurons in the substantia nigra with distinctive properties and embryonic origins. Cell Rep. 2021 Nov 9;37(6):109975 |
All: |
2 reference(s) |
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