Tg(TcraM25,TcrbM25)424Biat
Transgene Detail
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| Symbol: |
Tg(TcraM25,TcrbM25)424Biat |
| Name: |
transgene insertion 424, Biomodels Austria |
| MGI ID: |
MGI:7263388 |
| Synonyms: |
M25-II |
| Transgene: |
Tg(TcraM25,TcrbM25)424Biat Location: unknown
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| Alliance: |
Tg(TcraM25,TcrbM25)424Biat page
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| Transgene Type: |
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Transgenic (Inserted expressed sequence) |
| Mutation: |
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Insertion
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Tg(TcraM25,TcrbM25)424Biat expresses
2 genes
Transgene expresses:
| Organism |
Expressed Gene |
Note |
| mouse |
Tcra (MGI:98553) |
Expresses a Tcra clone specific for the M38-derived epitope of MCMV |
| mouse |
Tcrb (MGI:98578) |
Expresses a Tcrb clone specific for the M38-derived epitope of MCMV |
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Mutation details: This transgene expresses a mouse Tcra and Tcrb clone specific for the M25-derived epitope of MCMV, resulting in a percentage of M38-specific CD8 T cells among total nave CD8 T cells.
(J:195373)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:195373 Mandaric S, et al., IL-10 suppression of NK/DC crosstalk leads to poor priming of MCMV-specific CD4 T cells and prolonged MCMV persistence. PLoS Pathog. 2012;8(8):e1002846 |
| All: |
5 reference(s) |
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Analysis Tools
