Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Il15tm2Iku
Name:	interleukin 15; targeted mutation 2, Koichi Ikuta
MGI ID:	MGI:7263382
Synonyms:	IL-15fl, IL-15-floxed
Gene:	Il15  Location: Chr8:83058261-83129851 bp, - strand  Genetic Position: Chr8, 39.33 cM
Alliance:	Il15tm2Iku page

Germline Transmission:	Earliest citation of germline transmission: J:299923
Parent Cell Line:	KY1.1 (ES Cell)
Strain of Origin:	(C57BL/6J x 129S6/SvEvTac)F1

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion     LoxP sites were inserted into the gene. Further molecular details were not provided. (J:299923)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Il15 Mutation:	43 strains or lines available

Original:	J:299923 Zhu Y, et al., Intestinal epithelial cell-derived IL-15 determines local maintenance and maturation of intra-epithelial lymphocytes in the intestine. Int Immunol. 2020 May 8;32(5):307-319
All:	5 reference(s)