Tg(TcraM38,TcrbM38)329Biat
Transgene Detail
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| Symbol: |
Tg(TcraM38,TcrbM38)329Biat |
| Name: |
transgene insertion 329, Biomodels Austria |
| MGI ID: |
MGI:7263362 |
| Synonyms: |
M38 TCR-transgenic, Maxi, Tg(Tcra,Tcrb)329Biat |
| Transgene: |
Tg(TcraM38,TcrbM38)329Biat Location: unknown
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| Alliance: |
Tg(TcraM38,TcrbM38)329Biat page
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| Transgene Type: |
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Transgenic (Inserted expressed sequence) |
| Mutation: |
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Insertion
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Tg(TcraM38,TcrbM38)329Biat expresses
2 genes
Transgene expresses:
| Organism |
Expressed Gene |
Note |
| mouse |
Tcra (MGI:98553) |
Expresses a Tcra clone specific for the M38-derived epitope of MCMV |
| mouse |
Tcrb (MGI:98578) |
Expresses a Tcrb clone specific for the M38-derived epitope of MCMV |
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Mutation details: This transgene expresses a Tcra and Tcrb clone specific for the M38-derived epitope of MCMV. The "Maxi" mouse is transgenic for the rearranged M38 hybridoma Tcra and Tcrb chains, resulting in a percentage of M38-specific CD8 T cells among total nave CD8 T cells of around 90%.
(J:183174)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:183174 Torti N, et al., Non-hematopoietic cells in lymph nodes drive memory CD8 T cell inflation during murine cytomegalovirus infection. PLoS Pathog. 2011 Oct;7(10):e1002313 |
| All: |
12 reference(s) |
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Analysis Tools
