Tg(TcrbM38)330Biat
Transgene Detail
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| Symbol: |
Tg(TcrbM38)330Biat |
| Name: |
transgene insertion 330, Biomodels Austria |
| MGI ID: |
MGI:7263355 |
| Synonyms: |
Mini, Tg(Tcrb)330Biat |
| Transgene: |
Tg(TcrbM38)330Biat Location: unknown
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| Alliance: |
Tg(TcrbM38)330Biat page
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| Transgene Type: |
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Transgenic (Inserted expressed sequence) |
| Mutation: |
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Insertion
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Tg(TcrbM38)330Biat expresses
1 gene
Transgene expresses:
| Organism |
Expressed Gene |
Note |
| mouse |
Tcrb (MGI:98578) |
Expresses a Tcrb clone specific for the M38-derived epitope of MCMV |
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Mutation details: This transgene expresses a Tcrb clone specific for the M38-derived epitope of MCMV. The "Mini" mouse is transgenic for the rearranged hybridoma Tcrb chain only, which was expressed by nearly 100% of the CD8 T cells, while the Tcra chain is of endogenous origin. This increases the percentage of nave M38-specific CD8 T cells from undetectable levels in C57BL/6 mice to 10% of the total.
(J:183174)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:183174 Torti N, et al., Non-hematopoietic cells in lymph nodes drive memory CD8 T cell inflation during murine cytomegalovirus infection. PLoS Pathog. 2011 Oct;7(10):e1002313 |
| All: |
3 reference(s) |
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Analysis Tools
