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Tg(Lck-TLX1)13HAafo
Transgene Detail
Summary
Symbol: Tg(Lck-TLX1)13HAafo
Name: transgene insertion 13H, Adolfo A Ferrando
MGI ID: MGI:7262693
Synonyms: p56Lck-TLX1
Transgene: Tg(Lck-TLX1)13HAafo  Location: unknown  
Alliance: Tg(Lck-TLX1)13HAafo page
Transgene
origin
Strain of Origin:  (C57BL/6J x CBA/J)F1/J
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Lck-TLX1)13HAafo expresses 1 gene
 
Mutation detailsThe promoter drives T-cell-specific expression of the human sequence. Flp-mediated recombination removed the selection cassette. Three founder lines were generated. The pound symbol (#) is used when lines are pooled or no line is specified. (J:167561)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:167561 De Keersmaecker K, et al., The TLX1 oncogene drives aneuploidy in T cell transformation. Nat Med. 2010 Nov;16(11):1321-7
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory