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Gene Expression Data
Assay Details
Assay
Reference: J:316935 Chen Z, et al., DPPA2 and DPPA4 are dispensable for mouse zygotic genome activation and pre-implantation development. Development. 2021 Dec 15;148(24):dev200178
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7261224
Gene symbol: Dppa4
Gene name: developmental pluripotency associated 4
Results
Specimen 1B GV oocyte: postnatal adult (more )
Structure Level Pattern Image Note
TS28: primary oocyte Absent 1B Dppa4 GV oocyte
Specimen 1B 1-cell: embryonic day 0.5 (more )
Structure Level Pattern Image Note
TS1: 1-cell stage embryo Absent 1B Dppa4 1-cell
Specimen 1B Late 2-cell: embryonic day 1.0 (more )
Structure Level Pattern Image Note
TS2: 2-cell stage embryo Weak 1B Dppa4 Late 2-cell
Specimen 1B 4-cell: embryonic day 2.0 (more )
Structure Level Pattern Image Note
TS3: 4-cell stage embryo Present 1B Dppa4 4-cell
Specimen 1B 8-cell: embryonic day 2.5 (more )
Structure Level Pattern Image Note
TS3: 8-cell stage embryo Present 1B Dppa4 8-cell
Specimen 1B Morula: embryonic day 3.0 (more )
Structure Level Pattern Image Note
TS3: compacted morula Present 1B Dppa4 Morula
Specimen 1B Mid blastocyst: embryonic day 3.5 (more )
Structure Level Pattern Image Note
TS4: blastocyst Present 1B Dppa4 Mid blastocyst
Specimen 1B Late blastocyst: embryonic day 4.0 (more )
Structure Level Pattern Image Note
TS5: blastocyst Present 1B Dppa4 Late blastocyst
Specimen 1D left: embryonic day 3.5 (more )
Structure Level Pattern Image Note
TS4: inner cell mass Present 1D Dppa4 left
Specimen 1D right: embryonic day 3.5 (more )
Structure Level Pattern Image Note
TS4: inner cell mass Present 1D Dppa4 right
Specimen 2C m-z+Dppa2: embryonic day 2.0; Dppa2em1Yzhg/Dppa2+, Tg(Gdf9-icre)5092Coo/0 (more )
Note: Conditional mutant. maternal KO
Structure Level Pattern Image Note
TS3: 4-cell stage embryo Present 2C DPPA4 m-z+Dppa2
Specimen 2C m-z-Dppa2: embryonic day 2.0; Dppa2em1Yzhg/Dppa2em1Yzhg, Tg(Gdf9-icre)5092Coo/0 (more )
Note: Conditional mutant. maternal-zygotic KO
Structure Level Pattern Image Note
TS3: 4-cell stage embryo Weak 2C DPPA4 m-z-Dppa2 The Dppa4 signal was reduced in the Dppa2-maternal-zygotic KO.
Specimen 2C m-z+Dppa4: embryonic day 2.0; Dppa4tm1.2Yam/Dppa4+, Tg(Gdf9-icre)5092Coo/0 (more )
Note: Conditional mutant. maternal KO
Structure Level Pattern Image Note
TS3: 4-cell stage embryo Present 2C DPPA4 m-z+Dppa4 Dppa4 signal intensity in maternal KO 4-cell embryos was largely comparable to that of wild type embryos.
Specimen 2C m-z-Dppa4: embryonic day 2.0; Dppa4tm1.2Yam/Dppa4tm1.2Yam, Tg(Gdf9-icre)5092Coo/0 (more )
Note: Conditional mutant. maternal-zygotic KO
Structure Level Pattern Image Note
TS3: 4-cell stage embryo Absent 2C DPPA4 m-z-Dppa4
Specimen 3D m-z+Dppa2: embryonic day 3.5; Dppa2em1Yzhg/Dppa2+, Tg(Gdf9-icre)5092Coo/0 (more )
Note: Conditional mutant. maternal KO
Structure Level Pattern Image Note
TS4: inner cell mass Present 3D DPPA4 m-z+Dppa2
Specimen 3D m-z-Dppa2: embryonic day 3.5; Dppa2em1Yzhg/Dppa2em1Yzhg, Tg(Gdf9-icre)5092Coo/0 (more )
Note: Conditional mutant. maternal-zygotic KO
Structure Level Pattern Image Note
TS4: inner cell mass Weak 3D DPPA4 m-z-Dppa2
Specimen 3D m-z+Dppa4: embryonic day 3.5; Dppa4tm1.2Yam/Dppa4+, Tg(Gdf9-icre)5092Coo/0 (more )
Note: Conditional mutant. maternal KO
Structure Level Pattern Image Note
TS4: inner cell mass Present 3D DPPA4 m-z+Dppa4
Specimen 3D m-z-Dppa4: embryonic day 3.5; Dppa4tm1.2Yam/Dppa4tm1.2Yam, Tg(Gdf9-icre)5092Coo/0 (more )
Note: Conditional mutant. maternal-zygotic KO
Structure Level Pattern Image Note
TS4: inner cell mass Absent 3D DPPA4 m-z-Dppa4
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory