Runx1 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:322243 Fahl SP, et al., Loss of Ribosomal Protein Paralog Rpl22-like1 Blocks Lymphoid Development without Affecting Protein Synthesis. J Immunol. 2022 Feb 15;208(4):870-880
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:7261158
Gene symbol:	Runx1
Gene name:	runt related transcription factor 1

Antibody:

anti-Runx1

Results

Specimen 1 Rpl22l1 f/f: embryonic day 11.5; Rpl22l1^tm1Psam/Rpl22l1^tm1Psam (more

)
Note: Double labeled: green - Runx1; red - CD31 (Pecam1 assay MGI:7261159).

Structure	Cell Type	Level	Pattern	Image	Note
TS19: dorsal aorta	hematopoietic stem cell	Present		1_Rpl22l1 f/f

Specimen 1 Tie2-Cre Tg Rpl22l1 f/f: embryonic day 11.5; Rpl22l1^tm1Psam/Rpl22l1^tm1Psam, Tg(Tek-cre)1Ywa/0 (more

)
Note: Conditional mutant. Double labeled: green - Runx1; red - CD31 (Pecam1 assay MGI:7261159).

Structure	Level	Pattern	Image	Note
TS19: dorsal aorta	Ambiguous		1_Tie2-Cre Tg Rpl22l1 f/f	Authors reported attenutated emergence of hematopoietic stem cells.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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