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Gene Expression Data
Assay Details
Assay
Reference: J:311538 Zhang T, et al., Eya2 expression during mouse embryonic development revealed by Eya2(lacZ) knockin reporter and homozygous mice show mild hearing loss. Dev Dyn. 2021 Oct;250(10):1450-1462
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:7260326
Gene symbol: Eya2
Gene name: EYA transcriptional coactivator and phosphatase 2
Reporter: lacZ
Direct Detection
Results
Specimen 1E: embryonic day 10.5; Eya2tm2Px/Eya2+ (more )
Structure Level Pattern Image Note
TS17: Rathke's pouch Present 1E
TS17: dorsal root ganglion Present 1E
TS17: eye Present 1E
TS17: nose Present 1E
TS17: cranial nerve Present Regionally restricted 1E Expressed in the ocular (III) and trochlear (IV) motor neurons.
TS17: lens primordium Absent 1E
TS17: otocyst Absent 1E
TS17: facio-acoustic ganglion complex Strong 1E
TS17: glossopharyngeal ganglion Strong 1E
TS17: trigeminal ganglion Strong 1E
TS17: vagus ganglion Strong 1E
TS17: neural tube Present Regionally restricted 1E Expressed in the dorsal tip and migratory neural crest cells.
Specimen 1E': embryonic day 10.5; Eya2tm2Px/Eya2+ (more )
Structure Level Pattern Image Note
TS17: cranial nerve Present Regionally restricted 1E' upper , 1E' lower Expressed in the ocular (III) and trochlear (IV) motor neurons.
Specimen 1F: embryonic day 10.5; Eya2tm2Px/Eya2tm2Px (more )
Structure Level Pattern Image Note
TS17: Rathke's pouch Present 1F
TS17: dorsal root ganglion Present 1F
TS17: eye Present 1F
TS17: facio-acoustic ganglion complex Present 1F
TS17: glossopharyngeal ganglion Present 1F
TS17: nose Present 1F
TS17: trigeminal ganglion Present 1F
TS17: vagus ganglion Present 1F
TS17: cranial nerve Present Regionally restricted 1F Expressed in the ocular (III) and trochlear (IV) motor neurons.
TS17: neural tube Present Regionally restricted 1F Expressed in the dorsal tip and migratory neural crest cells.
Specimen 1F': embryonic day 10.5; Eya2tm2Px/Eya2tm2Px (more )
Structure Level Pattern Image Note
TS17: cranial nerve Present Regionally restricted 1F' Expressed in the ocular (III) and trochlear (IV) motor neurons.
Specimen 1G: embryonic day 9.5; Eya2tm2Px/Eya2+ (more )
Structure Level Pattern Image Note
TS15: dorsal root ganglion Present 1G
TS15: facio-acoustic preganglion complex Present 1G
TS15: nose Present 1G
TS15: trigeminal preganglion Present 1G
TS15: glossopharyngeal preganglion Weak 1G
TS15: vagus preganglion Weak 1G
Specimen 1G': embryonic day 9.5; Eya2tm2Px/Eya2+ (more )
Structure Level Pattern Image Note
TS15: facio-acoustic preganglion complex Present 1G'
TS15: fronto-nasal process ectoderm Present Regionally restricted 1G' Expressed in the invaginating olfactory epithelium.
TS15: trigeminal placode Present Regionally restricted 1G' Expressed in the ectoderm.
Specimen 1G": embryonic day 9.5; Eya2tm2Px/Eya2+ (more )
Structure Level Pattern Image Note
TS15: trigeminal preganglion Present 1G"
Specimen 1G"': embryonic day 9.5; Eya2tm2Px/Eya2+ (more )
Structure Level Pattern Image Note
TS15: facio-acoustic preganglion complex Present 1G"'
TS15: epibranchial placode Absent 1G"'
TS15: otocyst Absent 1G"'
Specimen 2A lacZ/+: embryonic day 12.5; Eya2tm2Px/Eya2+ (more )
Structure Level Pattern Image Note
TS20: dorsal root ganglion Present 2A left
TS20: eye Present 2A left
TS20: forelimb tendon primordium Present 2A left
TS20: oculomotor nerve Present 2A left
TS20: trigeminal ganglion Present 2A left
TS20: cranial nerve Present Regionally restricted 2A left Expressed in trochlear nerve.
TS20: nose Strong 2A left
Specimen 2A lacZ/lacZ: embryonic day 12.5; Eya2tm2Px/Eya2tm2Px (more )
Structure Level Pattern Image Note
TS20: dorsal root ganglion Present 2A right
TS20: eye Present 2A right
TS20: forelimb tendon primordium Present 2A right
TS20: oculomotor nerve Present 2A right
TS20: trigeminal ganglion Present 2A right
TS20: cranial nerve Present Regionally restricted 2A right Expressed in trochlear nerve.
TS20: nose Strong 2A right
Specimen 2B lacZ/+: embryonic day 14.5; Eya2tm2Px/Eya2+ (more )
Structure Level Pattern Image Note
TS22: olfactory epithelium Strong Regionally restricted 2B left Expressed in the basal neuronal progenitors but not in the apical layer of sustentacular cells.
Specimen 2B lacZ/lacZ: embryonic day 14.5; Eya2tm2Px/Eya2tm2Px (more )
Structure Level Pattern Image Note
TS22: olfactory epithelium Strong Regionally restricted 2B right Expressed in the basal neuronal progenitors but not in the apical layer of sustentacular cells.
Specimen 2C lacZ/+: embryonic day 14.5; Eya2tm2Px/Eya2+ (more )
Structure Level Pattern Image Note
TS22: olfactory epithelium Strong Regionally restricted 2C left Expressed in the basal neuronal progenitors but not in the apical layer of sustentacular cells.
TS22: vomeronasal organ Present 2C left
Specimen 2C lacZ/lacZ: embryonic day 14.5; Eya2tm2Px/Eya2tm2Px (more )
Structure Level Pattern Image Note
TS22: olfactory epithelium Strong Regionally restricted 2C right Expressed in the basal neuronal progenitors but not in the apical layer of sustentacular cells.
TS22: vomeronasal organ Present 2C right
Specimen 2D upper lacZ/+: embryonic day 12.5; Eya2tm2Px/Eya2+ (more )
Structure Level Pattern Image Note
TS20: eye mesenchyme Present Regionally restricted 2D upper left Expressed in mesenchymal cells surrounding optic stalk.
TS20: perioptic mesenchyme Present Regionally restricted 2D upper left Expressed in sclera.
TS20: lens primordium Absent 2D upper left
TS20: retina Present Regionally restricted 2D upper left Expressed in inner layer in the center.
Specimen 2D lower lacZ/+: embryonic day 12.5; Eya2tm2Px/Eya2+ (more )
Structure Level Pattern Image Note
TS20: extrinsic ocular pre-muscle mass Present 2D lower left
Specimen 2D upper lacZ/lacZ: embryonic day 12.5; Eya2tm2Px/Eya2tm2Px (more )
Structure Level Pattern Image Note
TS20: eye mesenchyme Present Regionally restricted 2D upper right Expressed in mesenchymal cells surrounding optic stalk.
TS20: retina Present Regionally restricted 2D upper right Expressed in inner layer in the center.
TS20: perioptic mesenchyme Present Regionally restricted 2D upper right Expressed in sclera.
TS20: lens primordium Absent 2D upper right
Specimen 2D lower lacZ/lacZ: embryonic day 12.5; Eya2tm2Px/Eya2tm2Px (more )
Structure Level Pattern Image Note
TS20: extrinsic ocular pre-muscle mass Present 2D lower right
TS20: retina Present Regionally restricted 2D lower right Expressed in inner layer in the center.
TS20: perioptic mesenchyme Present Regionally restricted 2D lower right Expressed in sclera.
Specimen 2E lacZ/+: embryonic day 14.5; Eya2tm2Px/Eya2+ (more )
Structure Level Pattern Image Note
TS22: retina Present Regionally restricted 2E left Expressed in inner layer.
TS22: perioptic mesenchyme Present Regionally restricted 2E left Expressed in sclera.
TS22: optic nerve Weak 2E left
TS22: eye mesenchyme Present Regionally restricted 2E left Expressed in mesenchymal cells surrounding optic stalk.
TS22: lens Absent 2E left
Specimen 2E lacZ/lacZ: embryonic day 14.5; Eya2tm2Px/Eya2tm2Px (more )
Structure Level Pattern Image Note
TS22: eye mesenchyme Present Regionally restricted 2E right Expressed in mesenchymal cells surrounding optic stalk.
TS22: retina Present Regionally restricted 2E right Expressed in inner layer.
TS22: perioptic mesenchyme Present Regionally restricted 2E right Expressed in sclera.
TS22: optic nerve Weak 2E right
TS22: lens Absent 2E right
Specimen 2F lacZ/+: embryonic day 12.5; Eya2tm2Px/Eya2+ (more )
Structure Level Pattern Image Note
TS20: central nervous system Present Regionally restricted 2F left Expressed in dorsal neural tube.
TS20: dorsal root ganglion Present 2F left
Specimen 2F lacZ/lacZ: embryonic day 12.5; Eya2tm2Px/Eya2tm2Px (more )
Structure Level Pattern Image Note
TS20: dorsal root ganglion Present 2F right
TS20: somite Present 2F right
TS20: central nervous system Present Regionally restricted 2F right Expressed in dorsal neural tube.
Specimen 3A lacZ/+: embryonic day 12.5; Eya2tm2Px/Eya2+ (more )
Structure Level Pattern Image Note
TS20: facial ganglion Present 3A left
TS20: glossopharyngeal ganglion Present 3A left
TS20: trigeminal ganglion Present 3A left
TS20: vagus ganglion Present 3A left
TS20: vestibulo-cochlear ganglion Present 3A left
TS20: central nervous system Present Regionally restricted 3A left Expressed in dorsal neural tube.
TS20: inner ear epithelium Absent 3A left
TS20: accessory nerve Weak 3A left
Specimen 3A lacZ/lacZ left: embryonic day 12.5; Eya2tm2Px/Eya2tm2Px (more )
Structure Level Pattern Image Note
TS20: central nervous system Present Regionally restricted 3A middle Expressed in dorsal neural tube.
TS20: accessory nerve Present 3A middle
TS20: facial ganglion Present 3A middle
TS20: glossopharyngeal ganglion Present 3A middle
TS20: trigeminal ganglion Present 3A middle
TS20: vagus ganglion Present 3A middle
TS20: vestibulo-cochlear ganglion Present 3A middle
TS20: inner ear epithelium Absent 3A middle
Specimen 3A lacZ/lacZ right: embryonic day 12.5; Eya2tm2Px/Eya2tm2Px (more )
Structure Level Pattern Image Note
TS20: facial ganglion Present 3A right
TS20: vestibulo-cochlear ganglion Present 3A right
TS20: inner ear epithelium Absent 3A right
Specimen 3B lacZ/+: embryonic day 14.5; Eya2tm2Px/Eya2+ (more )
Structure Level Pattern Image Note
TS22: utricle epithelium Present 3B left
TS22: vestibular ganglion Present 3B left
TS22: cochlea epithelium Weak Regionally restricted 3B left Expressed in the hair cells of the organ of Corti.
Specimen 3B lacZ/lacZ: embryonic day 14.5; Eya2tm2Px/Eya2tm2Px (more )
Structure Level Pattern Image Note
TS22: cochlea epithelium Weak Regionally restricted 3B right Expressed in the hair cells of the organ of Corti.
TS22: utricle epithelium Present 3B right
TS22: vestibular ganglion Present 3B right
Specimen 3C lacZ/lacZ left: embryonic day 15.5; Eya2tm2Px/Eya2tm2Px (more )
Structure Level Pattern Image Note
TS23: macula of utricle Present 3C left
TS23: vestibular component epithelium Present 3C left
TS23: semicircular canal epithelium Present Regionally restricted 3C left Expressed in differentiating hair cells in cristae ampullaris.
Specimen 3C lacZ/lacZ right: embryonic day 15.5; Eya2tm2Px/Eya2tm2Px (more )
Structure Level Pattern Image Note
TS23: macula of saccule Present 3C right
TS23: vestibular component epithelium Present 3C right
Specimen 3D lacZ/lacZ left: embryonic day 15.5; Eya2tm2Px/Eya2tm2Px (more )
Structure Level Pattern Image Note
TS23: cochlea epithelium Present Regionally restricted 3D left Stronger expression in the basal turn but weaker in the apical turns of the organ of Corit.
Specimen 3D lacZ/lacZ right: embryonic day 18.5; Eya2tm2Px/Eya2tm2Px (more )
Structure Level Pattern Image Note
TS26: cochlear duct epithelium Present Regionally restricted 3D right Stronger expression in both inner and outer hair cells throughout the cochlear duct.
Specimen 5A lacZ/+: embryonic day 12.5; Eya2tm2Px/Eya2+ (more )
Structure Level Pattern Image Note
TS20: oral region gland Weak Regionally restricted 5A left Expressed in parotid bud.
Specimen 5A lacZ/lacZ: embryonic day 12.5; Eya2tm2Px/Eya2tm2Px (more )
Structure Level Pattern Image Note
TS20: oral region gland Present Regionally restricted 5A right Weaker expression in submandibular bud and stronger in parotid bud.
Specimen 5B lacZ/+: embryonic day 14.5; Eya2tm2Px/Eya2+ (more )
Structure Level Pattern Image Note
TS22: salivary gland Present Regionally restricted 5B left Stronger expression in parotid duct and weaker in branching parotid gland.
Specimen 5B lacZ/lacZ: embryonic day 14.5; Eya2tm2Px/Eya2tm2Px (more )
Structure Level Pattern Image Note
TS22: salivary gland Present Regionally restricted 5B right Stronger expression in parotid duct and weaker in branching parotid gland.
Specimen 5C lacZ/+: embryonic day 14.5; Eya2tm2Px/Eya2+ (more )
Structure Level Pattern Image Note
TS22: salivary gland Present Regionally restricted 5C left Stronger expression in submandibular and sublingual duct and relatively weaker in sublingual gland.
Specimen 5C lacZ/lacZ: embryonic day 14.5; Eya2tm2Px/Eya2tm2Px (more )
Structure Level Pattern Image Note
TS22: salivary gland Present Regionally restricted 5C right Stronger expression in submandibular and sublingual duct and relatively weaker in branching submandibular and sublingual gland.
Specimen 5D lacZ/+: embryonic day 14.5; Eya2tm2Px/Eya2+ (more )
Structure Level Pattern Image Note
TS22: salivary gland Present Regionally restricted 5D left Expressed in branching submandibular gland.
Specimen 5D lacZ/lacZ: embryonic day 14.5; Eya2tm2Px/Eya2tm2Px (more )
Structure Level Pattern Image Note
TS22: salivary gland Present Regionally restricted 5D right Expressed in branching submandibular gland.
Specimen 6A lacZ/+: embryonic day 12.5; Eya2tm2Px/Eya2+ (more )
Structure Level Pattern Image Note
TS20: parathyroid primordium Present 6A left
TS20: thymus primordium Present 6A left
Specimen 6A lacZ/lacZ: embryonic day 12.5; Eya2tm2Px/Eya2tm2Px (more )
Structure Level Pattern Image Note
TS20: parathyroid primordium Present 6A right
TS20: thymus primordium Present 6A right
Specimen 6B lacZ/+ upper: embryonic day 14.5; Eya2tm2Px/Eya2+ (more )
Structure Level Pattern Image Note
TS22: esophagus Present 6B upper left
TS22: trachea Present 6B upper left
Specimen 6B lacZ/+ lower: embryonic day 14.5; Eya2tm2Px/Eya2+ (more )
Structure Level Pattern Image Note
TS22: esophagus Present 6B lower left
TS22: thymus primordium Present 6B lower left
TS22: trachea Present 6B lower left
Specimen 6B lacZ/lacZ upper: embryonic day 14.5; Eya2tm2Px/Eya2tm2Px (more )
Structure Level Pattern Image Note
TS22: esophagus Present 6B upper right
TS22: trachea Present 6B upper right
Specimen 6B lacZ/lacZ lower: embryonic day 14.5; Eya2tm2Px/Eya2tm2Px (more )
Structure Level Pattern Image Note
TS22: esophagus Present 6B lower right
TS22: thymus primordium Present 6B lower right
TS22: trachea Present 6B lower right
Specimen 6C lacZ/+: embryonic day 15.5; Eya2tm2Px/Eya2+ (more )
Structure Level Pattern Image Note
TS23: esophagus Present 6C left
TS23: thymus primordium Present 6C left
TS23: trachea Present 6C left
Specimen 6C lacZ/lacZ: embryonic day 15.5; Eya2tm2Px/Eya2tm2Px (more )
Structure Level Pattern Image Note
TS23: esophagus Present 6C right
TS23: thymus primordium Present 6C right
TS23: trachea Present 6C right
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory