Tg(CMV-m157)1Wyok
Transgene Detail
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| Symbol: |
Tg(CMV-m157)1Wyok |
| Name: |
transgene insertion 1, Wayne Yokoyama |
| MGI ID: |
MGI:7260259 |
| Synonyms: |
m157-Tg |
| Transgene: |
Tg(CMV-m157)1Wyok Location: unknown
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| Alliance: |
Tg(CMV-m157)1Wyok page
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| Strain of Origin: |
Not Specified
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| Transgene Type: |
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Transgenic (Inserted expressed sequence) |
| Mutation: |
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Insertion
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Mutation details: This trasngene expresses m157, which is the murine cytomegalovirus (MCMV)encoded ligand for the mouse Klra8 (Ly49H) NK cell activation receptor, under the control of a ubiquitous CMV promoter. The m157 ORF encodes a deduced 329-aa polypeptide. m157 contains a potential N-terminal 21-aa signal peptide, and an ectodomain with five potential sites for N-linked glycosylation. However, a putative hydrophobic transmembrane domain is interrupted by a stop codon. No line numbers were given.
(J:138607)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:138607 Tripathy SK, et al., Continuous engagement of a self-specific activation receptor induces NK cell tolerance. J Exp Med. 2008 Aug 4;205(8):1829-41 |
| All: |
9 reference(s) |
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Analysis Tools
