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Gene Expression Data
Assay Details
Assay
Reference: J:317272 Kuc CA, et al., Staufen 1 is expressed by neural precursor cells in the developing murine cortex but is dispensable for NPC self-renewal and neuronal differentiation in vitro. Brain Res. 2021 Dec 15;1773:147700
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7259771
Gene symbol: Stau1
Gene name: staufen double-stranded RNA binding protein 1
Antibody: Anti-Staufen/STAU1 antibody (ab73478)
Detection system: Secondary antibody coupled to Alexa Fluor 555
Results
Specimen 3Aiii-vii: embryonic day 12.0 (more )
Note: Double labeled: red - Stau1; green - Nes (assay MGI:7259775).
Structure Cell Type Level Pattern Image Note
TS20: cerebral cortex subventricular zone neural progenitor cell Strong 3Aiii , 3Aiv , 3Avii , 3Avi , 3Av Predominately cytoplasmic with a small amount of nuclear expression. Co-expressed with Nes in cell bodies of neural precursor cells.
TS20: cerebral cortex ventricular layer neural progenitor cell Strong 3Aiii , 3Aiv , 3Avii , 3Avi , 3Av Predominately cytoplasmic with a small amount of nuclear expression. Co-expressed with Nes in cell bodies of neural precursor cells.
TS20: cerebral cortex intermediate zone Present 3Aiii , 3Avi , 3Av , 3Aiv , 3Avii Much lower expression.
TS20: cortical plate Strong 3Aiv , 3Av , 3Aiii , 3Avii , 3Avi Predominately cytoplasmic with a small amount of nuclear expression.
Specimen 3Ax-xii: embryonic day 12.0 (more )
Note: Double labeled: red - Stau1; green - Tubb3 (assay MGI:7259777).
Structure Cell Type Level Pattern Image Note
TS20: cerebral cortex subventricular zone Strong 3Axii , 3Ax , 3Axi
TS20: cerebral cortex ventricular layer Strong 3Axii , 3Ax , 3Axi
TS20: cerebral cortex intermediate zone Present 3Axii , 3Axi , 3Ax Much lower expression.
TS20: cortical plate neural progenitor cell Strong 3Ax , 3Axii , 3Axi Co-expressed with Tubb3 in newly born neurons.
Specimen 3Biii-vii: embryonic day 18.0 (more )
Note: Double labeled: red - Stau1; green - Nes (assay MGI:7259775).
Structure Cell Type Level Pattern Image Note
TS26: cerebral cortex subventricular zone neural progenitor cell Strong 3Bv , 3Bvi , 3Bvii , 3Biii , 3Biv Predominately cytoplasmic with a small amount of nuclear expression. Co-expressed with Nes in cell bodies of neural precursor cells.
TS26: cerebral cortex ventricular layer neural progenitor cell Strong 3Bv , 3Bvi , 3Bvii , 3Biii , 3Biv Predominately cytoplasmic with a small amount of nuclear expression. Co-expressed with Nes in cell bodies of neural precursor cells.
TS26: cerebral cortex intermediate zone Present 3Biii , 3Bvii , 3Biv , 3Bvi , 3Bv Much lower expression.
TS26: cortical plate Strong 3Bvi , 3Biii , 3Bv , 3Biv , 3Bvii Predominately cytoplasmic with a small amount of nuclear expression.
Specimen 3Bx-xii: embryonic day 18.0 (more )
Note: Double labeled: red - Stau1; green - Tubb3 (assay MGI:7259777).
Structure Cell Type Level Pattern Image Note
TS26: cerebral cortex subventricular zone Strong 3Bxii , 3Bx , 3Bxi
TS26: cerebral cortex ventricular layer Strong 3Bxii , 3Bx , 3Bxi
TS26: cerebral cortex intermediate zone Present 3Bxi , 3Bxii , 3Bx Much lower expression.
TS26: cortical plate neural progenitor cell Strong 3Bxi , 3Bx , 3Bxii Co-expressed with Tubb3 in newly born neurons.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
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