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Gene Expression Data
Assay Details
Assay
Reference: J:168038 Bimonte S, et al., Ofd1 is required in limb bud patterning and endochondral bone development. Dev Biol. 2011 Jan 15;349(2):179-91
Assay type: RNA in situ
MGI Accession ID: MGI:7258480
Gene symbol: Pth1r
Gene name: parathyroid hormone 1 receptor
Probe: PPR probe3
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 8D: embryonic day 16.5 (more )
Structure Cell Type Level Pattern Image Note
TS24: ulna growth plate cartilage chondrocyte Present Regionally restricted 8D In proximal ulna, expression in prehypertrophic chondrocytes.
TS24: perichondrium Present 8D

Specimen 8E: embryonic day 16.5; Ofd1tm2.1Bfra/Ofd1+, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS24: ulna growth plate cartilage chondrocyte Present Regionally restricted 8E Normal expression in prehypertrophic chondrocytes compared to wildtype.
TS24: perichondrium Weak 8E Reduced expression in perichondrium.

Specimen 8F: embryonic day 16.5; Ofd1tm2.1Bfra/Y, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS24: ulna growth plate cartilage chondrocyte Present Regionally restricted 8F Normal expression in prehypertrophic chondrocytes compared to wildtype.
TS24: perichondrium Trace 8F Expression almost absent in perichondrium.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory