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Gene Expression Data
Assay Details
Assay
Reference: J:168038 Bimonte S, et al., Ofd1 is required in limb bud patterning and endochondral bone development. Dev Biol. 2011 Jan 15;349(2):179-91
Assay type: RNA in situ
MGI Accession ID: MGI:7258478
Gene symbol: Ihh
Gene name: Indian hedgehog
Probe: Ihh probe29
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 7A: embryonic day 16.5 (more )
Structure Cell Type Level Pattern Image Note
TS24: ulna growth plate cartilage chondrocyte Present Regionally restricted 7A In proximal ulna, expression in prehypertrophic chondrocytes.
TS24: perichondrium Present 7A
Specimen 7B: embryonic day 16.5; Ofd1tm2.1Bfra/Ofd1+, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS24: ulna growth plate cartilage chondrocyte Present Regionally restricted 7B Normal expression in prehypertrophic chondrocytes compared to wildtype.
TS24: perichondrium Weak 7B Reduced expression in perichondrium.
Specimen 7C: embryonic day 16.5; Ofd1tm2.1Bfra/Y, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS24: ulna growth plate cartilage chondrocyte Present Regionally restricted 7C Normal expression in prehypertrophic chondrocytes compared to wildtype.
TS24: perichondrium Trace 7C Expression almost absent in perichondrium.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory