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Gene Expression Data
Assay Details
Assay
Reference: J:168038 Bimonte S, et al., Ofd1 is required in limb bud patterning and endochondral bone development. Dev Biol. 2011 Jan 15;349(2):179-91
Assay type: RNA in situ
MGI Accession ID: MGI:7258467
Gene symbol: Ptch1
Gene name: patched 1
Probe: Ptch1 probe29
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen S5D: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: forelimb bud Present S5D
Specimen S5E: embryonic day 10.5; Ofd1tm2.1Bfra/Ofd1+, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: forelimb bud Present S5E Normal expression compared to wildtype.
Specimen S5F: embryonic day 10.5; Ofd1tm2.1Bfra/Y, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: forelimb bud Present S5F Normal expression compared to wildtype.
Specimen 4D: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: forelimb bud Present Regionally restricted 4D Expression in cells adjacent to Shh expression domain.
Specimen 4E: embryonic day 11.5; Ofd1tm2.1Bfra/Ofd1+, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: forelimb bud Weak Regionally restricted 4E Expression downregulated compared with wildtype.
Specimen 4F: embryonic day 11.5; Ofd1tm2.1Bfra/Y, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: forelimb bud Trace 4F Expression almost absent.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/30/2025
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