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Gene Expression Data
Assay Details
Assay
Reference: J:320845 Yu M, et al., Genome-Wide Association Study-Driven Gene-Set Analyses, Genetic, and Functional Follow-Up Suggest GLIS1 as a Susceptibility Gene for Mitral Valve Prolapse. Circ Genom Precis Med. 2019 May;12(5):e002497
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7258346
Gene symbol: Glis1
Gene name: GLIS family zinc finger 1
Antibody: anti-Glis1
Detection system: Secondary antibody
Results
Specimen 4 E13.5: embryonic day 13.5 (more )
Note: Double labeled: red - Glis1; green - MF20 marking sarcomeric myosin-myocytes.
Structure Level Pattern Image Note
TS21: mitral valve Present Regionally restricted 4_left Expressed in nuclei of endothelial cells of the valves, as well as the valvular interstitial cells.
Specimen 4 E17.5: embryonic day 17.5 (more )
Note: Double labeled: red - Glis1; green - MF20 marking sarcomeric myosin-myocytes.
Structure Level Pattern Image Note
TS25: mitral valve leaflet Present Regionally restricted 4_middle Expressed in a subset of endocardial and interstitial cells.
Specimen 4 6m: postnatal month 6 (more )
Note: Double labeled: red - Glis1; green - MF20 marking sarcomeric myosin-myocytes.
Structure Level Pattern Image Note
TS28: mitral valve Weak Regionally restricted 4_right Much weaker expression with only scant cytoplasmic staining in endocardial cells.
Specimen not shown: postnatal month 6 (more )
Structure Level Pattern Image Note
TS28: cardiac muscle tissue Weak
TS28: ventricle endocardial lining Weak
TS28: visceral pericardium Weak
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/30/2024
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