About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:248919 Yu W, et al., Irx1 regulates dental outer enamel epithelial and lung alveolar type II epithelial differentiation. Dev Biol. 2017 Sep 1;429(1):44-55
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7258179
Gene symbol: Sox2
Gene name: SRY (sex determining region Y)-box 2
Results
Specimen 8A Irx1+/+: embryonic day 18.5 (more )
Note: Triple labeled: red - Sox2; green - Lef1 (assay MGI:7258178); blue - DAPI.
Structure Level Pattern Image Note
TS26: cervical loop Present Regionally restricted 8A Irx1+/+ (merge) , 8A Irx1+/+ Sox2 In cap stage teeth, expression localized to labial cervical loop region.
TS26: lower jaw incisor Present Regionally restricted 8A Irx1+/+ (merge) , 8A Irx1+/+ Sox2 In cap stage teeth, expression localized to labial cervical loop region.

Specimen 8A Irx1-/-: embryonic day 18.5; Irx1tm1(KOMP)Vlcg/Irx1tm1(KOMP)Vlcg (more )
Note: Triple labeled: red - Sox2; green - Lef1 (assay MGI:7258178); blue - DAPI.
Structure Level Pattern Image Note
TS26: lower jaw incisor Present Regionally restricted 8A Irx1-/- (merge) , 8A Irx1-/- Sox2 Expression in lingual region close to oral epithelium.

Specimen 8B: embryonic day 18.5 (more )
Note: Triple labeled: red - Sox2; green - Irx1 (assay MGI:7258176); blue - DAPI.
Structure Level Pattern Image Note
TS26: lower jaw incisor Present 8B Sox2

Specimen 8B (inset): embryonic day 18.5 (more )
Note: Triple labeled: red - Sox2; green - Irx1 (assay MGI:7258176); blue - DAPI.
Structure Level Pattern Image Note
TS26: lower jaw incisor Present 8B inset


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
05/28/2024
MGI 6.13
The Jackson Laboratory