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Gene Expression Data
Assay Details
Assay
Reference: J:248919 Yu W, et al., Irx1 regulates dental outer enamel epithelial and lung alveolar type II epithelial differentiation. Dev Biol. 2017 Sep 1;429(1):44-55
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7258179
Gene symbol: Sox2
Gene name: SRY (sex determining region Y)-box 2
Results
Specimen 8A Irx1+/+: embryonic day 18.5 (more )
Note: Triple labeled: red - Sox2; green - Lef1 (assay MGI:7258178); blue - DAPI.
Structure Level Pattern Image Note
TS26: cervical loop Present Regionally restricted 8A Irx1+/+ (merge) , 8A Irx1+/+ Sox2 In cap stage teeth, expression localized to labial cervical loop region.
TS26: lower jaw incisor Present Regionally restricted 8A Irx1+/+ (merge) , 8A Irx1+/+ Sox2 In cap stage teeth, expression localized to labial cervical loop region.
Specimen 8A Irx1-/-: embryonic day 18.5; Irx1tm1(KOMP)Vlcg/Irx1tm1(KOMP)Vlcg (more )
Note: Triple labeled: red - Sox2; green - Lef1 (assay MGI:7258178); blue - DAPI.
Structure Level Pattern Image Note
TS26: lower jaw incisor Present Regionally restricted 8A Irx1-/- (merge) , 8A Irx1-/- Sox2 Expression in lingual region close to oral epithelium.
Specimen 8B: embryonic day 18.5 (more )
Note: Triple labeled: red - Sox2; green - Irx1 (assay MGI:7258176); blue - DAPI.
Structure Level Pattern Image Note
TS26: lower jaw incisor Present 8B Sox2
Specimen 8B (inset): embryonic day 18.5 (more )
Note: Triple labeled: red - Sox2; green - Irx1 (assay MGI:7258176); blue - DAPI.
Structure Level Pattern Image Note
TS26: lower jaw incisor Present 8B inset
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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