Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Trp63tm1.1Gml
Name:	transformation related protein 63; targeted mutation 1.1, Gerry Melino
MGI ID:	MGI:7258079
Synonyms:	delta13p63
Gene:	Trp63  Location: Chr16:25502513-25710838 bp, + strand  Genetic Position: Chr16, 17.37 cM
Alliance:	Trp63tm1.1Gml page

Germline Transmission:	Earliest citation of germline transmission: J:300878
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Modified isoform(s)) Mutations:    Insertion, Intragenic deletion   Mutation details: The targeting construct floxed exon 13. Cre-mediated recombination removed exon 13. This allele only expresses isoform beta. (J:300878)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Trp63 Mutation:	60 strains or lines available

Original:	J:300878 Lena AM, et al., The p63 C-terminus is essential for murine oocyte integrity. Nat Commun. 2021 Jan 15;12(1):383
All:	1 reference(s)